Results 11 to 20 of about 13,099 (249)

Radiolabeled Nanocarriers as Theranostics—Advancement from Peptides to Nanocarriers

open access: yesSmall, 2022
AbstractEndogenous targeted radiotherapy is emerging as an integral modality to treat a variety of cancer entities. Nevertheless, despite the positive clinical outcome of the treatment using radiolabeled peptides, small molecules, antibodies, and nanobodies, a high degree of hepatotoxicity and nephrotoxicity still persist.
Prachi Desai   +6 more
openaire   +6 more sources

Chaperonins: Nanocarriers with Biotechnological Applications [PDF]

open access: yesNanomaterials, 2021
Chaperonins are molecular chaperones found in all kingdoms of life, and as such they assist in the folding of other proteins. Structurally, chaperonins are cylinders composed of two back-to-back rings, each of which is an oligomer of ~60-kDa proteins.
Sergio Pipaón   +7 more
openaire   +6 more sources

Apoferritin as an ubiquitous nanocarrier with excellent shelf life [PDF]

open access: yes, 2017
Due to many adverse effects of conventional chemotherapy, novel methods of targeting drugs to cancer cells are being investigated. Nanosize carriers are a suitable platform for this specific delivery.
David Hynek   +19 more
core   +2 more sources

Nanocarrier-Assisted Delivery of Metformin Boosts Remodeling of Diabetic Periodontal Tissue via Cellular Exocytosis-Mediated Regulation of Endoplasmic Reticulum Homeostasis

open access: yes, 2022
Endoplasmic reticulum (ER) dysfunction is a potential contributor to the impaired repair capacity of periodontal tissue in diabetes mellitus (DM) patients.
Lanxin Yang (13982164)   +12 more
core   +1 more source

Raman Imaging of Nanocarriers for Drug Delivery

open access: yesNanomaterials, 2019
The efficacy of pharmaceutical agents can be greatly improved through nanocarrier delivery. Encapsulation of pharmaceutical agents into a nanocarrier can enhance their bioavailability and biocompatibility, whilst also facilitating targeted drug delivery ...
Sally Vanden-Hehir   +5 more
doaj   +1 more source

A CXCR4-targeted nanocarrier achieves highly selective tumor uptake in diffuse large B-cell lymphoma mouse models

open access: yesHaematologica, 2020
One-third of diffuse large B-cell lymphoma patients are refractory to initial treatment or relapse after rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone chemotherapy.
Aïda Falgàs   +12 more
doaj   +1 more source

Gene Therapy Using Nanocarriers for Pancreatic Ductal Adenocarcinoma: Applications and Challenges in Cancer Therapeutics

open access: yesPharmaceutics, 2022
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide, and its incidence is increasing. PDAC often shows resistance to several therapeutic modalities and a higher recurrence rate after surgical treatment in the early ...
Eun-Jeong Won   +3 more
doaj   +1 more source

Food Antimicrobials Nanocarriers [PDF]

open access: yesThe Scientific World Journal, 2014
Natural food antimicrobials are bioactive compounds that inhibit the growth of microorganisms involved in food spoilage or food-borne illness. However, stability issues result in degradation and loss of antimicrobial activity. Nanoencapsulation allows protection of antimicrobial food agents from unfavorable environmental conditions and ...
Adriana Blanco-Padilla   +3 more
openaire   +3 more sources

Evaluation of Carboxymethyl-Hexanoyl Chitosan as a Protein Nanocarrier [PDF]

open access: yes, 2013
Carboxymethyl‐hexanoyl chitosan (CHC) has the ability to self‐assemble into nanocapsules in an aqueous solution and it has recently shown potential in numerous biomedical applications.
Mikael Larsson   +21 more
core   +1 more source

Developing a novel cholesterol-based nanocarrier with high transfection efficiency and serum compatibility for gene therapy

open access: yesJournal of the Formosan Medical Association, 2019
Background/Purpose: Primary cells are sensitive to culture conditions, which can be more difficult to get efficient transfection. The purpose of this study is to develop a serum-compatible cholesterol-based nanocarrier for delivering therapeutic nucleic ...
Karen Chang   +2 more
doaj   +1 more source

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