Results 91 to 100 of about 12,080 (272)

Improvement of therapeutic efficacy of PLGA nanoformulation of siRNA targeting anti-apoptotic Bcl-2 through chitosan coating

, 2013
Potential use of siRNA as therapeutic agent has elicited a great deal of interest. However, insufficient cellular uptake and poor stability limited its application in therapeutics.
Jagani, Hitesh Vitthalbhai, Gang, Sagar Shantimal, Palanimuthu, Vasanth Raj; id_orcid, Hariharapura, Raghu Chandrashekar, Josyula, Venkata Rao   +4 more
core   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Anticancer Evaluation of Methoxy Poly(Ethylene Glycol)-b-Poly(Caprolactone) Polymeric Micelles Encapsulating Fenbendazole and Rapamycin in Ovarian Cancer

International Journal of Nanomedicine, 2023
Yu Been Shin,1,* Ju-Yeon Choi,2,* Dae Hwan Shin,1 Jeong-Won Lee2,3 1College of Pharmacy, Chungbuk National University, Cheongju, 28160, Republic of Korea; 2Research Institute for Future Medicine, Samsung Medical Center, Sungkyunkwan University ...
Shin YB, Choi JY, Shin DH, Lee JW
doaj  

Quality by Design for the Nanoformulation of Cosmeceuticals

Pharmaceutics
Cosmeceuticals are cosmetic formulations that are intended to alleviate skin conditions that affect its appearance and functionality. They are not considered medications but contain molecules that exert biological action on the skin beyond traditional cosmetic actions.
Gerardo Leyva-Gómez, Elizabeth Piñón-Segundo, Zaida Urban-Morlan, Nancy E. Magaña-Vergara, David Quintanar-Guerrero, Betzabeth Jaime-Escalante, Néstor Mendoza-Muñoz   +6 more
openaire   +3 more sources

Au2Pt-PEG-Ce6 nanoformulation with dual nanozyme activities for synergistic chemodynamic therapy / phototherapy

, 2020
Although synergistic therapy for tumors has displayed significant promise for effective treatment of cancer, developing a simple and effective strategy to build a multi-functional nanoplatform is still a huge challenge.
Mengyu Chang, Bengang Xing, Jin, D, Zhiyao Hou, Jun Lin, Dongmei Wang, Xing, B, Qing Chen, Wang, D, Li, C, Lin, J, Chen, Q, Hou, Z, Wang, M, Dayong Jin, Chunxia Li, Man Wang, Chang, M   +17 more
core   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Asymmetric Mesoporous Nanoformulation for Combination Treatment of Soft Tissue Sarcoma

Soft tissue sarcoma (STS) is a kind of tumor that is difficult to treat by chemotherapy alone. In recent years, various studies have been conducted on the use of multifunctional nanoparticles with core@shell or indiscriminate coassembly to improve ...
Minchao Liu (9977001), Meng Fang (473455), Weiluo Cai (9197906), Xiaomin Li (207257), Peihang Xu (8279931), Mo Cheng (9197903), Wangjun Yan (9197909), Tiancong Zhao (4277587)   +7 more
core   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Inhibitory Effect of Nano-Formulated Extract of Passiflora incarnata on Dalton’s Lymphoma Ascites-Bearing Swiss albino Mice

Pharmaceutics
Background/Objectives: This study explored the antitumor effect of Passiflora incarnata leaves’ nanoformulation (N-EEP) in fibroblasts, A375 cell lines, and in vivo using Dalton’s lymphoma ascites (DLA)-bearing mice.
Balasubramanian Deepika, Gopalarethinam Janani, Devadass Jessy Mercy, Saranya Udayakumar, Agnishwar Girigoswami, Koyeli Girigoswami   +5 more
doaj   +1 more source

Neuroprotective effects of nanoformulated Paraboea leuserensis B.L.Burtt on memory loss and depression in traumatic brain injury–induced rats: Behavioral and molecular insights [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Traumatic brain injury (TBI) is a major neurological disorder leading to memory loss and depression due to neuroinflammation and neuronal damage.
Syafruddin Ilyas, Yurnadi Hanafi Midoen, Safni Safni   +2 more
doaj   +1 more source