Results 51 to 60 of about 3,520 (152)
Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen +8 more
wiley +1 more source
A novel nanoluciferase transgenic reporter measures proteinuria in zebrafish
The zebrafish is an important animal system for modeling human diseases. This includes kidney dysfunction as the embryonic kidney (pronephros) shares considerable molecular and morphological homology with the human nephron.
Naylor, Richard W.; id_orcid +6 more
core +1 more source
Workflow for BICC1 interactome characterization in HEK293T cells. Cells expressing FLAG‐tagged BICC1 (full‐length or ΔSAM) were subjected to co‐immunoprecipitation under RNA‐preserved (−) or RNase‐treated (+) conditions (1). Interacting proteins were identified by LC–MS/MS (2) and analyzed through protein–protein interaction networks and functional ...
Heloísa Monteiro do Amaral‐Prado +7 more
wiley +1 more source
Generation of Trypanosoma cruzi Colombiana parasites expressing nanoluciferase.
(A) Schematic representation of pBEX-NLuc and its integration into the T. cruzi ribosomal RNA gene locus by homologous recombination. 18SA and 18SB: T.
Stenio Perdigão Fragoso (218271) +4 more
core +1 more source
Nanoluciferase-Based Method for Detecting Gene Expression in Caenorhabditis elegans [PDF]
Genetic reporters such as the green fluorescent protein (GFP) can facilitate measurement of promoter activity and gene expression. However, animal autofluorescence limits the sensitivity of GFP and other fluorescent reporters in whole-animal settings ...
Sfarcic, Ivana +3 more
core +1 more source
Membrane‐Associated Biomolecules for Synthetic Cell Signalling
Membrane‐associated proteins and nucleic acids are transforming synthetic cell communication, unlocking applications in biosensing, therapeutics, and tissue engineering. This review explores how these biomolecules enable complementary strategies for cell tethering, vesicle generation and fusion, signal transmission, and signal transduction.
Chelsea Dack +3 more
wiley +1 more source
Fleet normalization with nanoluciferase in whole blood.
Raw data is provided for the fleet titration in whole blood (Fig 2B). The full set of luminometers was used to perform a simultaneous titration of nanoluciferase in order to normalize the sensitivity of all devices.
Axel Jacobsen (18004487) +12 more
core +1 more source
Organometallic Complex Strongly Impairs Chikungunya Virus Entry to the Host Cells
Chikungunya fever is a disease caused by the Chikungunya virus (CHIKV) that is transmitted by the bite of the female of Aedes sp. mosquito. The symptoms include fever, muscle aches, skin rash, and severe joint pains.
Débora Moraes de Oliveira +15 more
doaj +1 more source
Transgenic luciferase-expressing Plasmodium falciparum parasites have been widely used for the evaluation of anti-malarial compounds. Here, to screen for anti-malarial drugs effective against multiple stages of the parasite, we generate a P.
Yukiko Miyazaki +11 more
doaj +1 more source
Integrated Immunological Engineering Platform for Scalable Production of iPSC‐Derived Megakaryocytes
ABSTRACT Severe thrombocytopenia and impaired platelet function remain major clinical challenges in hematologic diseases, chemotherapy, bone marrow failure, surgery and obstetric haemorrhage. Conventional platelet transfusions are limited by donor dependency, short shelf life, storage constraints, and immune‐mediated platelet refractoriness caused ...
Rabea Dettmer +6 more
wiley +1 more source

