Results 291 to 300 of about 65,196 (347)

Long-range PCR and Nanopore sequencing for localisation and phasing variants: an end-to-end clinical application workflow. [PDF]

BMC Med Genomics
Jamshidi J, Rowntree C, Fadaee S, Zhang F, Zhu Y, Buckley M, Hart F, Roscioli T.   +7 more
europepmc   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

The FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini, Hira Khursheed, Wen Wei Zhang, Isabelle Aubry, Greg Matlashewski, Michel L. Tremblay, Patrick Lypaczewski   +6 more
wiley   +1 more source

High-throughput and Efficient Assay for Central Nervous System Infection with Targeted Nanopore Sequencing Technology. [PDF]

Infect Drug Resist
Shi Y, Lin Z, Chen Z, Ye C, Yu J, Xi J, Geng Y, Zou M, Ren H, Wang L, Wang B, Xu F, Zheng X, Xiang G.   +13 more
europepmc   +1 more source

Gonorrhea Management in High‐, Limited‐ and No‐Resource Settings: Implications in the Context of Antimicrobial Resistance

International Journal of Dermatology, EarlyView.
ABSTRACT Gonorrhea, a common sexually transmitted infection caused by Neisseria gonorrhoeae, represents an escalating global public health threat due to antimicrobial resistance. The current review explores diverse approaches around the globe to gonorrhea management across various settings, with a focus on diagnostic strategies, treatment practices ...
Andrei Tanasov, Maciej Pastuszczak, George‐Sorin Tiplica   +2 more
wiley   +1 more source

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

A new compression strategy to reduce the size of nanopore sequencing data. [PDF]

Genome Res
Jayasooriya K, Jenner SP, Marasinghe P, Senanayake U, Saadat H, Taubman D, Ragel R, Gamaarachchi H, Deveson IW.   +8 more
europepmc   +1 more source

Genome assembly of the Bos gaurus in Vietnam using nanopore sequencing. [PDF]

BMC Genom Data
Nguyen TDT, Tran TBN, Nguyen LT.
europepmc   +1 more source

Whole-genome nanopore sequencing and automatic downstream analysis of respiratory syncytial virus using RSVTyper. [PDF]

Sci Rep
Le DB, Tometten I, Lübke N, Paluschinski M, Schupp AK, Ehlkes L, Kreuzer P, Zacharias N, Timm J, Dilthey A, Walker A.   +10 more
europepmc   +1 more source