Results 231 to 240 of about 47,549 (275)

Accu16S/AccuITS: Accurate and broadly applicable amplicon sequencing for absolute microbiome quantification

iMeta, EarlyView.
Traditional 16S rRNA gene and Internal Transcribed Spacer region amplicon sequencing provides only relative abundance, often leading to biased ecological interpretations. To overcome this limitation, we developed Accu16S/AccuITS, an absolute quantification method for bacterial and fungal amplicons based on synthetic internal spike‐in DNA with known ...
Defeng Bai, Ou Fang, Caihua Li, Bin Cai, Xingyan Tan, Mengmeng Jiang, Bin Gan, Jinxia Fu, Yunyun Gao, Ying Wang, Yong‐Xin Liu   +10 more
wiley   +1 more source

Elucidating the Mechanisms of Ion Permeation through Sub-Nanometer Graphene Pores: Uncovering Free Energy Barriers via High-Throughput Molecular Simulations. [PDF]

ACS Nano
Ordorica AF, Cheng P, Chaturvedi P, Cummings PT, Kidambi PR.   +4 more
europepmc   +1 more source

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

iMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji, Haochen Li, Qi Wang, Xiaojuan Wang, Jiawei Zhang, Ying Xiao, Huan Li, Hao Liu, Tanqing Long, Boyang Wu, Hao Chen, Haoming Xia, Xinquan Liu, Chuanrui Xu, Yibo Gao, Bingjun Tang, Juan Liu, Shizhong Yang, Jiahong Dong   +18 more
wiley   +1 more source

DNA aggregation and resolubilization in the presence of polyamines probed at the single molecule level using nanopores. [PDF]

Chem Sci
Cai Y, Cressiot B, Balme S, Raspaud E, Bacri L, Pelta J.   +5 more
europepmc   +1 more source

Incorporation of Butanol into Nanopores of Syndiotactic Polystyrene. [PDF]

Polymers (Basel)
Fujino S, Miyauchi R, Nakaoki T, Rizzo P.   +3 more
europepmc   +1 more source

Cellulose hydrogel with in-situ confined nanopores for boosting moist-electric conversion. [PDF]

Nat Commun
Lin X, Tao S, Mo J, Wang X, Shao Y, Hu Y, Qiu C, Shen K, Dang C, Qi H.   +9 more
europepmc   +1 more source

Engineering Linker-Enhanced OmpG Nanopores for Rapid Single-Molecule Protease Detection. [PDF]

Sensors (Basel)
Kim M, Pham B.
europepmc   +1 more source

Insights to Resistive Pulse Sensing of Microparticle and Biological Cells on Microfluidic Chip. [PDF]

Biosensors (Basel)
Yao Y, Zhao K, Jia H, Wei Z, Huo Y, Zhang Y, Zhang K.   +6 more
europepmc   +1 more source

Peptide properties predict multistate translocation kinetics via protective antigen nanopores. [PDF]

Biophys J
Colby JM, Krantz BA.
europepmc   +1 more source

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Nanopore sequencing technology: nanopore preparations

Trends in Biotechnology, 2007
For the past decade, nanometer-scale pores have been developed as a powerful technique for sensing biological macromolecules. Various potential applications using these nanopores have been reported at the proof-of-principle stage, with the eventual aim of using them as an alternative to de novo DNA sequencing.
Minsoung, Rhee, Mark A, Burns
openaire   +2 more sources