Formulation and development of Tacrolimus nanosponges-loaded hydrogel for the treatment of atopic dermatitis [PDF]
Targeted drug delivery to specific locations is a significant challenge encountered by researchers. Nanosponges have emerged as a promising solution for delivering drugs to their target sites.
Borse Janhavi D +3 more
doaj +4 more sources
Cyclodextrin-based nanosponges as drug carriers [PDF]
Cyclodextrin-based nanosponges, which are proposed as a new nanosized delivery system, are innovative cross-linked cyclodextrin polymers nanostructured within a three-dimensional network.
Francesco Trotta +2 more
doaj +7 more sources
Preparation and investigation of a novel combination of Solanum nigrum-loaded, arabinoxylan-cross-linked β-cyclodextrin nanosponges for the treatment of cancer: in vitro, in vivo, and in silico evaluation [PDF]
Introduction: Cancer contributes to a high mortality rate worldwide spanning its diversity from genetics to resistant therapeutic response. To date emerging strategies to combat and manage cancer are particularly focused on the development of targeted ...
Hamid Saeed Shah +8 more
doaj +4 more sources
Magnetic Composites of Dextrin-Based Carbonate Nanosponges and Iron Oxide Nanoparticles with Potential Application in Targeted Drug Delivery [PDF]
Magnetically driven nanosponges with potential application as targeted drug delivery systems were prepared via the addition of magnetite nanoparticles to the synthesis of cyclodextrin and maltodextrin polymers crosslinked with 1,1′-carbonyldiimidazole ...
Fabrizio Caldera +5 more
doaj +2 more sources
Encapsulation of Babchi Oil in Cyclodextrin-Based Nanosponges: Physicochemical Characterization, Photodegradation, and In Vitro Cytotoxicity Studies [PDF]
Babchi (Psoralea corylifolia) oil is an important essential oil used in several traditional medicines to cure various disorders. This phytotherapeutic agent possesses a number of pharmacological activities including antibacterial, antifungal, antioxidant,
Sunil Kumar +3 more
doaj +2 more sources
Developing Novel Hydroxypropyl-β-Cyclodextrin-Based Nanosponges as Carriers for Anticancer Hydrophobic Agents: Overcoming Limitations of Host–Guest Complexes in a Comparative Evaluation [PDF]
This study aimed to design and fabricate novel hydroxypropyl-β-cyclodextrin-based hypercrosslinked polymers, called nanosponges, as carriers for anticancer hydrophobic agents and compare them with host–guest complexes of hydroxypropyl-β-cyclodextrin, a ...
Shohreh Peimanfard +5 more
doaj +2 more sources
Comparative Evaluation of Solubility, Cytotoxicity and Photostability Studies of Resveratrol and Oxyresveratrol Loaded Nanosponges [PDF]
Resveratrol and oxyresveratrol are natural polyphenolic stilbenes with several important pharmacological activities. However, low solubility and aqueous instability are the major limitations in their drug delivery applications.
Nilesh Kumar Dhakar +8 more
doaj +3 more sources
Engineered Porous Beta-Cyclodextrin-Loaded Raloxifene Framework with Potential Anticancer Activity: Physicochemical Characterization, Drug Release, and Cytotoxicity Studies [PDF]
Jana K Alwattar,1,2 Mohammed M Mehanna3,4 1Department of Pharmaceutical Sciences, School of Pharmacy, Lebanese International University, Beirut, Lebanon; 2Pharmaceutical Nanotechnology Research Lab, Faculty of Pharmacy, Beirut Arab University, Beirut ...
Alwattar JK, Mehanna MM
doaj +2 more sources
A Novel Biomimetic Nanosponge Protects the Retina from the
Intraocular infections are a potentially blinding complication of common ocular surgeries and traumatic eye injuries. Bacterial toxins synthesized in the eye can damage intraocular tissue, often resulting in poor visual outcomes.
Austin L. LaGrow +8 more
doaj +2 more sources
Nanosponge: A promising and intriguing strategy in medical and pharmaceutical Science [PDF]
The complicated chemical reactions involved in the production of the newer drug delivery systems have mainly impeded efforts to build successful targeted drug delivery systems for a prolonged duration of time.
Akash Garg +6 more
doaj +2 more sources

