Results 41 to 50 of about 2,413 (208)

Preparation and investigation of a novel combination of Solanum nigrum-loaded, arabinoxylan-cross-linked β-cyclodextrin nanosponges for the treatment of cancer: in vitro, in vivo, and in silico evaluation

Frontiers in Pharmacology, 2023
Introduction: Cancer contributes to a high mortality rate worldwide spanning its diversity from genetics to resistant therapeutic response. To date emerging strategies to combat and manage cancer are particularly focused on the development of targeted ...
Hamid Saeed Shah, Sumera Zaib, Imtiaz Khan, Mahmoud A. Sliem, Osama Alharbi, Mohammed Al-Ghorbani, Zobia Jawad, Kiran Shahzadi, Sajjad Awan   +8 more
doaj   +1 more source

Nanosponges : Formulation And Evaluation Of Nanosponges

International Journal of Advanced Research in Science, Communication and Technology
This review aims that the study of to formulate and evaluate nonosponges as a Novel drug delivery systems, exploiting their potential to improve the biological availability of drug with long half lives. Nanosponges, tiny mesh structure with enhanced ability to encapsulate water and lipid soluble drug, have gained significant attention in the field of ...
null Ms. Samiksha S. Shendre, null Ms. Shreya B. Bhale, null Ms. Sakshi R. Shinde, null Ms. Purva A. Daware, null Ms. Bhagyashri P. Devakr, null Ms. Vaishnavi D. Chavan, null Prof. S. W. Gawande, null Dr. M. D. Kitukale   +7 more
openaire   +1 more source

A Novel Biomimetic Nanosponge Protects the Retina from the Enterococcus faecalis Cytolysin

mSphere, 2017
Intraocular infections are a potentially blinding complication of common ocular surgeries and traumatic eye injuries. Bacterial toxins synthesized in the eye can damage intraocular tissue, often resulting in poor visual outcomes.
Austin L. LaGrow, Phillip S. Coburn, Frederick C. Miller, Craig Land, Salai Madhumathi Parkunan, Brian T. Luk, Weiwei Gao, Liangfang Zhang, Michelle C. Callegan   +8 more
doaj   +1 more source

Formulation and in-vivo evaluation of nanosponges based tramadol HCL C/R tablets using design of experiment [PDF]

, 2022
The current study was aimed to develop a controlled release formulation of tramadol utilizing the cyclodextrin based nanosponges. Box-Behnken design was employed to study the effect of each independent variable on dependent variables.
Rao, Ambati Sambashiva, Reddy, D. V. (Duggi), Rao, A. S. (Ambati), Reddy, Duggi Vamshidhar, Duggi Vamshidhar Reddy, Ambati Sambashiva Rao   +5 more
core   +1 more source

Nanocarrier Systems in Taste Masking

Scientia Pharmaceutica, 2022
Taste is the most crucial organoleptic parameter affecting patient compliance in the case of drugs with poor palatability. Taste masking is a major challenge for the development of orally ingested active pharmaceutical constituents in the pharmaceutical ...
Nasr Eldin Hussein Nasr, Aliaa Nabil ElMeshad, Ahmed Roshdy Fares   +2 more
doaj   +1 more source

Nanosponges: A New Drug Delivery System [PDF]

, 2019
Frustrated from the complex chemistry of the drugs have troubled the researchers in finding the ideal drug. Effective targeted drug delivery system has always been the dream.
Mandan, Savita, Chavan, Maitreyee, Bhadane, Yamini, Kalal, Chetan   +3 more
core   +1 more source

Formulation and evaluation of cyclodextrin-based nanosponges of griseofulvin as pediatric oral liquid dosage form for enhancing bioavailability and masking bitter taste

Saudi Pharmaceutical Journal, 2020
The aim of this study was the development of griseofulvin (GRI) loaded β-cyclodextrin (β–CD) based nanosponges for bitter taste masking, improving dissolution rate and oral bioavailability. Plain NS (NS1 NS2 and NS3) were fabricated by reacting β-CD with
Samia M. Omar, Fares Ibrahim, Aliaa Ismail   +2 more
doaj   +1 more source

Self‐Adaptive Biomimetic Nanocomposite Hydrogel Orchestrates Dual‐Targeting and On‐Demand H2S Gasotransmission for Multifactorial Diabetic Wound Therapy

Advanced Science, EarlyView.
A self‐adaptive and biomimetic nanocomposite hydrogel is engineered to orchestrate dual‐targeting and on‐demand H2S gasotransmission for multifactorial diabetic wound therapy. By seamlessly integrating antibacterial, antioxidant, anti‐inflammatory, immunoregulatory, and pro‐angiogenic functions within a single platform, this hydrogel dynamically ...
Kefan Wu, Xiaoxue Yang, Yonghang Liu, Yi Xiao, Shiyu Meng, Ao Li, Yi Zhun Zhu, Hui Guo, Xiaolin Wang   +8 more
wiley   +1 more source

Nanosponge Tunability in Size and Crosslinking Density [PDF]

Journal of Visualized Experiments, 2017
We describe a protocol for the synthesis of linear polyesters containing pendant epoxide functionality and their incorporation into a nanosponge with controlled dimensions. This approach begins with synthesis of a functionalized lactone which is key to the pendant functionalization of the resulting polymer.
Laken L, Kendrick-Williams, Eva, Harth
openaire   +2 more sources

NANOSPONGES: A NEW ERA OF VERSATILE DRUG DELIVERY SYSTEM [PDF]

, 2017
Nanotechnology is a multi disciplinary science which is getting considerable attention in development of new chemical entities, diagnosis and treatment of several ailments.
Kumar, Kapil, rahi, Neha, null null, Neha rahi   +3 more
core   +1 more source