Results 51 to 60 of about 1,307 (174)

Mechanochemical green synthesis of hyper-crosslinked cyclodextrin polymers

Beilstein Journal of Organic Chemistry, 2020
Cyclodextrin nanosponges (CD-NS) are nanostructured crosslinked polymers made up of cyclodextrins. The reactive hydroxy groups of CDs allow them to act as multifunctional monomers capable of crosslinking to bi- or multifunctional chemicals.
Alberto Rubin Pedrazzo, Fabrizio Caldera, Marco Zanetti, Silvia Lucia Appleton, Nilesh Kumar Dhakar, Francesco Trotta   +5 more
doaj   +1 more source

Ribociclib-Loaded Ethylcellulose-Based Nanosponges: Formulation, Physicochemical Characterization, and Cytotoxic Potential against Breast Cancer

Adsorption Science & Technology, 2022
In the present study, ribociclib-loaded nanosponges (RCNs) composed of ethylcellulose and polyvinyl alcohol were developed using an emulsion-solvent evaporation method.
Mohammed Muqtader Ahmed, Farhat Fatima, Amer Alali, Mohd Abul Kalam, Khalid Alhazzani, Saurabh Bhatia, Sultan Alshehri, Mohammed M. Ghoneim   +7 more
doaj   +1 more source

Development and Characterization of Ibrutinib-Loaded Ethylcellulose-Based Nanosponges: Cytotoxicity Assay against MCF-7 Cell Lines

Applied Sciences, 2023
Ibrutinib (ITB) is a specific and novel irreversible inhibitor of Bruton’s tyrosine kinase enzyme, for which reason it exhibits potential chemotherapeutic effects against a few types of B-cell cancers.
Farhat Fatima, Md. Khalid Anwer
doaj   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Cell membrane‐coated nanoparticles for dermatological diseases

VIEW, Volume 7, Issue 3, June 2026.
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley   +1 more source

Formulation and development of Tacrolimus nanosponges-loaded hydrogel for the treatment of atopic dermatitis

Current Issues in Pharmacy and Medical Sciences
Targeted drug delivery to specific locations is a significant challenge encountered by researchers. Nanosponges have emerged as a promising solution for delivering drugs to their target sites.
Borse Janhavi D, Pawar Ashish Y, Bendkule Kanchan B, Shinde Prajwal S   +3 more
doaj   +1 more source

Label‐Free SERS Fingerprinting of Neuroprotein Conformational Dynamics in Human Saliva

Advanced Materials, Volume 38, Issue 28, 18 May 2026.
Galvanic molecular entrapment (GME) is a label‐free method for detecting and quantifying neuroprotein conformational states. This technique enables direct surface binding and in situ hotspot generation around molecules, effectively overcoming challenges related to target localization and mismatched hotspot geometries.
Muhammad Shalahuddin Al Ja'farawy, Jun‐Yeong Yang, Chaewon Mun, Seunghun Lee, Chul Bum Cho, Yoo Hyun Um, Min‐Young Lee, Sung‐Gyu Park, Dong‐Ho Kim, Seung Ho Yang, Ho Sang Jung   +10 more
wiley   +1 more source

Simultaneous Laser Reduction of Sn/Sb Salts and Graphene Formation as Innovative Anode Material for Li‐ and Na‐Ion Batteries

Global Challenges, Volume 10, Issue 5, May 2026.
A novel, scalable method for laser‐induced graphene–metal composite anodes for Li‐ion and Na‐ion batteries fabrication is reported. Embedded Sn, Sb, and Sn‐Sb alloy nanoparticles in graphene are created, which can accommodate volume changes during cycling, enhancing stability and rate performance.
Vincenzo Vezzoni, Michele Setti, Giacomo Magnani, Laura Fornasini, Silvio Scaravonati, Alessia Rinaldi, Niyaz Ahmad, Lorenzo Pasetti, Danilo Bersani, Giovanni Bertoni, Michele Sidoli, Gioele Genovese, Mauro Riccò, Daniele Pontiroli   +13 more
wiley   +1 more source

Enhanced therapeutic approach for diabetic foot ulcers: comparative study and characterisation of mupirocin-loaded nanosponge gel with marketed formulation for accelerating wound healing and in vivo evaluation

Future Journal of Pharmaceutical Sciences
Background The current investigation aimed to develop, optimise, and assess a mupirocin-loaded nanosponge-based topical delivery system for diabetic foot ulcer and to achieve prolonged drug release while improving drug deposition within the skin.
Rushikesh S. Dhamak, Pramod S. Salve, Deepak R. Tiwari, Pradnya A. Raut, Darshan S. Waghmare   +4 more
doaj   +1 more source

PSMA‐Targeting Macrophage Membrane‐Coated Nanoparticles for Precision Diagnosis and Combination Therapy of Prostate Cancer

Exploration, Volume 6, Issue 2, April 2026.
Advanced prostate cancer is highly invasive and prone to rapid metastasis, creating an urgent need for novel therapeutic strategies. We developed a PSMA‐targeting macrophage membrane‐coated nanomedicine (P‐MMCNPs@DM1). Leveraging the immune‐evasive and active‐targeting properties of macrophage membrane coating, P‐MMCNPs@DM1 effectively managed both ...
Keying Zhang, Bo Gao, Jingwei Wang, Yu Li, Chao Xu, Fa Yang, Shaojie Liu, Hongji Li, Chao Zhang, Xiangliang Meng, Zhaokun Shi, Rui Zhang, Ruili Zhang, Zhongliang Wang, Weihong Wen, Qiang Zhang, Yuankang Zou, Donghui Han, Huijie Bian, Weijun Qin   +19 more
wiley   +1 more source