Results 61 to 70 of about 2,413 (208)

DESIGN, DEVELOPMENT AND EVALUATION OF DILTIAZEM HYDROCHLORIDE LOADED NANOSPONGES FOR ORAL DELIVERY [PDF]

open access: yes, 2020
Objective: In the current investigation,nanosponges were set up by emulsion solvent diffusion technique utilizing ethyl cellulose and β-cyclodextrin as polymers.
RAO, B. NARASIMHA   +3 more
core   +1 more source

Nanomedicine for the Treatment of Pediatric Type 2 Diabetes: Progress, Challenges, and Translational Perspectives

open access: yesAdvanced Therapeutics, Volume 9, Issue 9, September 2026.
Overview of pharmaceutical nanocarriers in diabetes, illustrating applications of nanotechnology including enhanced drug and targeted drug delivery and nanosensors for glucose monitoring and diagnosis. ABSTRACT Pediatric type 2 diabetes mellitus (T2DM) is rapidly emerging as a critical global health concern, driven largely by rising childhood obesity ...
Nnamdi Ikemefuna Okafor   +2 more
wiley   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

open access: yesAgriFood: Journal of Agricultural Products for Food, Volume 2, Issue 3, Page 262-284, September 2026.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John   +4 more
wiley   +1 more source

FORMULATION AND EVALUATION OF IBRUTINIB NANOSPONGES INCOPORATED TABLET

open access: yes, 2023
Objective: The present investigation was undertaken to prepare polymeric nanosponges of an anti-cancer drug, ibrutinib to achieve controlled and improved drug release.
BHIKSHAPATHI, D. V. R. N.   +4 more
core   +1 more source

Mechanochemical green synthesis of hyper-crosslinked cyclodextrin polymers

open access: yesBeilstein Journal of Organic Chemistry, 2020
Cyclodextrin nanosponges (CD-NS) are nanostructured crosslinked polymers made up of cyclodextrins. The reactive hydroxy groups of CDs allow them to act as multifunctional monomers capable of crosslinking to bi- or multifunctional chemicals.
Alberto Rubin Pedrazzo   +5 more
doaj   +1 more source

Ribociclib-Loaded Ethylcellulose-Based Nanosponges: Formulation, Physicochemical Characterization, and Cytotoxic Potential against Breast Cancer

open access: yesAdsorption Science & Technology, 2022
In the present study, ribociclib-loaded nanosponges (RCNs) composed of ethylcellulose and polyvinyl alcohol were developed using an emulsion-solvent evaporation method.
Mohammed Muqtader Ahmed   +7 more
doaj   +1 more source

Development and Characterization of Ibrutinib-Loaded Ethylcellulose-Based Nanosponges: Cytotoxicity Assay against MCF-7 Cell Lines

open access: yesApplied Sciences, 2023
Ibrutinib (ITB) is a specific and novel irreversible inhibitor of Bruton’s tyrosine kinase enzyme, for which reason it exhibits potential chemotherapeutic effects against a few types of B-cell cancers.
Farhat Fatima, Md. Khalid Anwer
doaj   +1 more source

A Strontium‐Based Polyphenol Nanozyme Reverses Cisplatin‐Related Acute Kidney Injury Through Near‐Infrared‐Enhanced PI3K/AKT Pathway Inhibition and Macrophage M2 Directional Polarization

open access: yesRare Metals, Volume 45, Issue 9, September 2026.
ABSTRACT Cisplatin‐related acute kidney injury (CP‐AKI) is a serious complication of cisplatin (CP) treated patients with cancer with high morbidity and mortality rates. It is directly related to the abnormal accumulation of CP in renal tubular epithelial cells, causing metabolic toxicity, DNA damage, and oxidative stress.
Minghe Jiang   +12 more
wiley   +1 more source

Immunomodulatory Nanozymes as Programmable Redox–Immune Set‐Point Regulators

open access: yesSmall, Volume 22, Issue 53, 21 September 2026.
Conceptual phase space linking reactive oxygen species level/dynamics to immune state, with pathological set‐points for chronic inflammation, tumor escape, and degeneration contrasted against a central healthy redox–immune set‐point. Buffering and amplifying nanozymes are depicted as devices that dial redox tone up or down to steer diseased ...
Sumi Choi   +3 more
wiley   +1 more source

Natural Pigments and Cyclodextrins: Overview on a Synergistic Approach to Encapsulation

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT The growing demand for natural dyes in the food industry has stimulated research into strategies aimed at improving their stability, solubility, and bioavailability. This review examines the synergistic use of cyclodextrins (CDs) as encapsulating agents for natural pigments, highlighting their ability to form inclusion complexes that protect ...
Chiara Pippolini   +3 more
wiley   +1 more source

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