Results 31 to 40 of about 1,307 (174)

Preparation and investigation of a novel combination of Solanum nigrum-loaded, arabinoxylan-cross-linked β-cyclodextrin nanosponges for the treatment of cancer: in vitro, in vivo, and in silico evaluation

Frontiers in Pharmacology, 2023
Introduction: Cancer contributes to a high mortality rate worldwide spanning its diversity from genetics to resistant therapeutic response. To date emerging strategies to combat and manage cancer are particularly focused on the development of targeted ...
Hamid Saeed Shah, Sumera Zaib, Imtiaz Khan, Mahmoud A. Sliem, Osama Alharbi, Mohammed Al-Ghorbani, Zobia Jawad, Kiran Shahzadi, Sajjad Awan   +8 more
doaj   +1 more source

NANOSPONGES: A REVIEW

International Journal of Applied Pharmaceutics, 2018
The recent advance in nanotechnology has lead to the development of targeted drug delivery system. However, targeting a molecule to a particular site using a drug delivery system effectively requires a specialized drug delivery system. The discovery of nanosponge has become a significant step in overcoming certain problems such as drug toxicity, poor ...
Himangshu Bhowmik, D. Nagasamy Venkatesh, Anuttam Kuila, Kammari Harish Kumar   +3 more
openaire   +2 more sources

Nanosponges : Formulation And Evaluation Of Nanosponges

International Journal of Advanced Research in Science, Communication and Technology
This review aims that the study of to formulate and evaluate nonosponges as a Novel drug delivery systems, exploiting their potential to improve the biological availability of drug with long half lives. Nanosponges, tiny mesh structure with enhanced ability to encapsulate water and lipid soluble drug, have gained significant attention in the field of ...
null Ms. Samiksha S. Shendre, null Ms. Shreya B. Bhale, null Ms. Sakshi R. Shinde, null Ms. Purva A. Daware, null Ms. Bhagyashri P. Devakr, null Ms. Vaishnavi D. Chavan, null Prof. S. W. Gawande, null Dr. M. D. Kitukale   +7 more
openaire   +1 more source

A Novel Biomimetic Nanosponge Protects the Retina from the Enterococcus faecalis Cytolysin

mSphere, 2017
Intraocular infections are a potentially blinding complication of common ocular surgeries and traumatic eye injuries. Bacterial toxins synthesized in the eye can damage intraocular tissue, often resulting in poor visual outcomes.
Austin L. LaGrow, Phillip S. Coburn, Frederick C. Miller, Craig Land, Salai Madhumathi Parkunan, Brian T. Luk, Weiwei Gao, Liangfang Zhang, Michelle C. Callegan   +8 more
doaj   +1 more source

Nanocarrier Systems in Taste Masking

Scientia Pharmaceutica, 2022
Taste is the most crucial organoleptic parameter affecting patient compliance in the case of drugs with poor palatability. Taste masking is a major challenge for the development of orally ingested active pharmaceutical constituents in the pharmaceutical ...
Nasr Eldin Hussein Nasr, Aliaa Nabil ElMeshad, Ahmed Roshdy Fares   +2 more
doaj   +1 more source

Formulation and evaluation of cyclodextrin-based nanosponges of griseofulvin as pediatric oral liquid dosage form for enhancing bioavailability and masking bitter taste

Saudi Pharmaceutical Journal, 2020
The aim of this study was the development of griseofulvin (GRI) loaded β-cyclodextrin (β–CD) based nanosponges for bitter taste masking, improving dissolution rate and oral bioavailability. Plain NS (NS1 NS2 and NS3) were fabricated by reacting β-CD with
Samia M. Omar, Fares Ibrahim, Aliaa Ismail   +2 more
doaj   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source

Optical Plasmons of Individual Gold Nanosponges [PDF]

ACS Photonics, 2015
The search for novel plasmonic nanostructures, which can act simultaneously as optical detectors and stimulators, is crucial for many applications in the fields of biosensing, electro- and photocatalysis, electrochemistry, and biofuel generation. In most of these areas, a large surface-to-volume ratio, as well as high density of active surface sites ...
Cynthia Vidal, Dong Wang, Peter Schaaf, Calin Hrelescu, Thomas A. Klar   +4 more
openaire   +2 more sources

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

Small, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung, Gargi Yogesh Digholkar, Ryan M. Pearson   +2 more
wiley   +1 more source

In Vitro Enhanced Skin Permeation and Retention of Imiquimod Loaded in β-Cyclodextrin Nanosponge Hydrogel

Pharmaceutics, 2019
Imiquimod (IMQ) is an immune response modifier clinically used for the treatment of various topical diseases. However, its poor aqueous solubility and skin penetration capability make the topical delivery of IMQ a challenging task.
Monica Argenziano, Adam Haimhoffer, Chiara Bastiancich, László Jicsinszky, Fabrizio Caldera, Francesco Trotta, Sara Scutera, Daniela Alotto, Mara Fumagalli, Tiziana Musso, Carlotta Castagnoli, Roberta Cavalli   +11 more
doaj   +1 more source