Results 21 to 30 of about 1,307 (174)

Synthesis and evaluation of B-cyclodextrin Based Nanosponges of 5- Fluorouracil by Using Ultrasound Assisted Method

Iraqi Journal of Pharmaceutical Sciences, 2020
CD-nanosponges were prepared by crosslinking B-CD with diphenylcarbonate (DPC) using ultrasound assisted technique. 5-FU was incorporated with NS by freeze drying, and the phase solubility study, complexation efficiency (CE) entrapment efficiency were ...
Ihsan K. Jasim, Shaimaa N. Abd Alhammid, Alaa A. Abdulrasool   +2 more
doaj   +1 more source

Effect of Ni/Rh ratios on characteristics of NixRhy nanosponges towards high-performance hydrogen evolution reaction

Data in Brief, 2019
The data presented in this article are related to the research article entitled “NiRh Nanosponges with Highly Efficient Electrocatalytic Performance for Hydrogen Evolution Reaction (N.-A. Nguyen et al., 2019) [1].
Ngoc-Anh Nguyen, Ho-Suk Choi
doaj   +1 more source

Weak complexation of 5-fluorouracil with β-cyclodextrin, carbonate, and dianhydride crosslinked β-cyclodextrin: in vitro and in silico studies

Research in Pharmaceutical Sciences, 2022
Background and purpose: Several pharmaceutical formulations were investigated to improve the solubility of 5-fluorouracil to enhance bioavailability and therapeutic efficacy. This study aimed to examine the potential use of cyclodextrin-based nanosponges
Hadeia Mashaqbeh, Rana Obaidat, Nizar A Al-Shar’i, Tamam El-Elimat, Soraya Alnabulsi   +4 more
doaj   +1 more source

Glutathione Bioresponsive Cyclodextrin Nanosponges [PDF]

ChemPlusChem, 2015
AbstractCyclodextrin‐based nanosponges are designed as new nanostructured material for drug delivery. In vitro and in vivo studies show that nanosponges can increase the effectiveness of anti‐cancer drugs encapsulated within their nanostructure. Reported is a new, cheap glutathione (GSH)‐responsive material easily obtained in high yield through a one ...
Francesco, Trotta, Fabrizio, Caldera, Chiara, Dianzani, Monica, Argenziano, Giuseppina, Barrera, Roberta, Cavalli   +5 more
openaire   +3 more sources

Comparative Evaluation of Solubility, Cytotoxicity and Photostability Studies of Resveratrol and Oxyresveratrol Loaded Nanosponges

Pharmaceutics, 2019
Resveratrol and oxyresveratrol are natural polyphenolic stilbenes with several important pharmacological activities. However, low solubility and aqueous instability are the major limitations in their drug delivery applications.
Nilesh Kumar Dhakar, Adrián Matencio, Fabrizio Caldera, Monica Argenziano, Roberta Cavalli, Chiara Dianzani, Marco Zanetti, José Manuel López-Nicolás, Francesco Trotta   +8 more
doaj   +1 more source

Optimisation of a Greener-Approach for the Synthesis of Cyclodextrin-Based Nanosponges for the Solubility Enhancement of Domperidone, a BCS Class II Drug

Pharmaceuticals, 2023
BCS class II molecules suffer from low oral bioavailability because of their poor permeability and sub-optimal aqueous solubility. One of the approaches to enhance their bioavailability is using cyclodextrin-based nanosponges.
Mohit Vij, Neha Dand, Lalit Kumar, Pankaj Wadhwa, Shahid Ud Din Wani, Wael A. Mahdi, Sultan Alshehri, Prawez Alam, Faiyaz Shakeel   +8 more
doaj   +1 more source

β-Cyclodextrin Nanosponges for Oral Drug Delivery of Anti-Hypertensive Drug

Medical Sciences Forum, 2022
Nicardipine (NC) is an antihypertensive drug indicated for treatment of high blood pressure and angina. It belongs to BCS class-II, having poor solubility and low oral bioavailability.
Ritika Prashant Khivansara, Sandhya Bajirao Jadhav, Varsha Daund, Atul Sherje   +3 more
doaj   +1 more source

Encapsulation of Babchi Oil in Cyclodextrin-Based Nanosponges: Physicochemical Characterization, Photodegradation, and In Vitro Cytotoxicity Studies

Pharmaceutics, 2018
Babchi (Psoralea corylifolia) oil is an important essential oil used in several traditional medicines to cure various disorders. This phytotherapeutic agent possesses a number of pharmacological activities including antibacterial, antifungal, antioxidant,
Sunil Kumar, Pooja, Francesco Trotta, Rekha Rao   +3 more
doaj   +1 more source

Solubility and dissolution rate enhancement of ibuprofen by cyclodextrin based carbonate nanosponges

Pakistan Journal of Pharmaceutical Sciences, 2021
In the present study nanotechnology approach, i.e., a cyclodextrin (CD) based carbonate nanosponge was used to improve the solubility and dissolution of ibuprofen.
Qurat-ul-ain Shoaib, Sumera Latif, Qazi Amir Ijaz, Hafsa Afzal, Muhammad Irfan Siddique, Amjad Hussain, Muhammad Sohail Arshad, Nadeem Irfan Bukhari, Nasir Abbas   +8 more
doaj   +1 more source

A Review on Nanosponges

International Journal of Indigenous Herbs and Drugs
The development of targeted drug delivery systems has faced challenges due to the complex chemical reactions involved. However, nano-sponges, a newly developed colloidal system, show promise in overcoming issues such as drug toxicity, poor bioavailability, and inconsistent drug release.
Simhadri Dasari, Raj Kumar K, Babu Rao Chandu   +2 more
openaire   +2 more sources