Results 31 to 40 of about 71,184 (302)

Nap-spermine, an agonist of spermine receptor TAAR348, induced responses virtually identical to those induced by spermine.

open access: yes, 2019
(A) Nap-spermine induced cAMP production in a concentration-dependent manner in TAAR348-expressing HEK293T cells (mean ± SEM, n = 5). The cAMP assay was done as in Fig 3B. (Inset) Structure of nap-spermine. (B) EOG responses to 10−7 M spermine and 10−7 M
Edmund Ellsworth (6934163)   +11 more
core   +1 more source

ryokbys/nap: v0.10.14

open access: yes, 2022
implemented RFMEAM potential. implemented strain control using deform entry.
RYO KOBAYASHI
core   +1 more source

Gerontechnologies for Home Support [PDF]

open access: yes
No Abstract. This is an Edited book containing an introduction by the Authors (Moreno, Helal, Nap and Gutman), in addition to a number of articles curated and reviewed by the Authors with help provided by external ...
S. Nap, G. Gutman, A. Helal, A. Moreno
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Success in the Natural Detection Task is influenced by only a few factors generally believed to affect dogs’ olfactory performance

open access: yesScientific Reports
Research into dogs' olfactory ability is growing rapidly. However, generalising based on scientific results is challenging, because research has been typically conducted on a few specially trained subjects of a few breeds tested in different ...
Attila Salamon   +7 more
doaj   +1 more source

NAP model

open access: yes, 2022
Nucleus Attraction Principle (NAP): models, experimental data and a ...
Aviad Albert, Bruno Nicenboim
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Network Automatic Pruning: Start NAP and Take a Nap

open access: yesCoRR, 2021
Network pruning can significantly reduce the computation and memory footprint of large neural networks. To achieve a good trade-off between model size and performance, popular pruning techniques usually rely on hand-crafted heuristics and require manually setting the compression ratio for each layer.
Wenyuan Zeng   +2 more
openaire   +2 more sources

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli   +13 more
wiley   +1 more source

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