Results 91 to 100 of about 29,168 (237)

Anti-inflammatory and osteogenic effects of naringenin

, 2020
In the U.S., over half of the elderly population is afflicted with osteoporosis and low bone density (1). Osteoporosis can be defined as a bone disease that results in bone loss and fragility.
Carswell, Savion
core   +1 more source

Naringenin: A potential therapeutic agent for modulating angiogenesis and immune response in hepatocellular carcinoma

Journal of Pharmaceutical Analysis
Naringenin (4,5,7-trihydroxyflavonoid) is a naturally occurring bioflavonoid found in citrus fruits, which plays an important role in metabolic syndrome, neurological disorders, and cardiovascular diseases.
Wenmei Wu, Xiangyu Qiu, Xiaofan Ye, Zhiliang Zhang, Siguo Xu, Xiuqi Yao, Yinyi Du, Geyan Wu, Rongxin Zhang, Jinrong Zhu   +9 more
doaj   +1 more source

Naringenin Modifies the Development of Lineage-Specific Effector CD4+ T Cells

Frontiers in Immunology, 2018
Disrupted balance in the lineages of CD4+ T cell subsets, including pro-inflammatory T helper (Th) cells and anti-inflammatory regulatory T cells (Treg), is a primary pathogenic factor for developing autoimmunity. We have found that this immunomodulatory
Junpeng Wang, Xinli Niu, Chunfang Wu, Dayong Wu   +3 more
doaj   +1 more source

Synthesis of isoprenoid naringenin derivatives

, 2020
5 Abstract Charles University, Faculty of Pharmacy in Hradec Králové Department Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Candidate Jakub Kernal Supervisor prof. PharmDr. Consultant Hubert Chapuis, Ph.D. Title of Thesis Synthesis
Kernal, Jakub
core  

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds

The Chemical Record, EarlyView.
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá, Patrick C. Nobre, Isabelly O. Ferreira, Juliano B. Azeredo, Vanessa Nascimento   +4 more
wiley   +1 more source

Oral Ulcerations and Phytotherapy: Potential Role of Helichrysum Essential Oil—A Literature Review

Oral Diseases, EarlyView.
ABSTRACT Background Recurrent aphthous stomatitis (RAS) is a common yet therapeutically challenging chronic inflammatory disease of the oral mucosa, characterized by recurrent, painful ulcerations that substantially affect patients' quality of life. Objective This review summarizes current evidence on phytotherapy in RAS, with particular focus on the ...
Ruzica Ivkovic, Reka Antic, Avisek Majumder, Suravi Majumder, Dragana Stanisic   +4 more
wiley   +1 more source

An in-vitro exploration of the antifibrotic activity of Naringenin: A potential therapeutic agent for oral submucous fibrosis management

Journal of Oral Biology and Craniofacial Research
Background: Oral submucous fibrosis (OSMF) is a precancerous condition primarily associated with betel nut chewing. Naringenin, a flavonoid found in citrus fruits, has been demonstrated to show antifibrotic effects in various fibrosis models. The present
S. Samyuktha Aarthi, Deepak Pandiar, Raghunandhakumar Subramanian, Reshma Poothakulath Krishnan   +3 more
doaj   +1 more source

Integrated Metabolomics and Selection Signal Analysis Provide Insights Into the Selection for Flavonol Biosynthesis Associated With Lettuce Quality Improvement

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lettuce is a critical leafy vegetable consumed worldwide and is a substantial dietary source of health‐promoting compounds. Exploring changes in metabolism during lettuce domestication under artificial selection conditions is important to facilitate further breeding and cultivation for quality improvement.
Xiao Yang, Shiwei Wei, Ge Jin, Li Zhang, Ran Du, Yajun Wang, Chengcheng Shen, Tao Huang, Guotao Huo, Jie Peng, Bo Song, Fangyuan Zhang, Victor Hugo Escalona Contreras, Lijun Luo, Yuejian Li, Francisco A. Tomas‐Barberan, Bin Liu, Qichang Yang   +17 more
wiley   +1 more source

The TaCOMT1A‐Synthesised Sakuranetin Is a Novel Biostimulant Enhancing Drought Tolerance and Yield in Wheat

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought stress is a major limitation to global wheat production. Here, we demonstrate that the wheat gene TaCOMT1A, encoding a caffeic acid O‐methyltransferase, plays a crucial role in enhancing drought tolerance in wheat. Overexpression of TaCOMT1A significantly improved drought tolerance at the seedling stage, as evidenced by higher survival
Mingzhao Luo, Chengjie Xu, Wenjing Yang, Wensi Tang, Kai Chen, Jiaqing Guo, Qiyu Wang, Jun Chen, Zhaoshi Xu, Pierre Delaplace, Youzhi Ma, Yongbin Zhou, Ming Chen   +12 more
wiley   +1 more source