Results 71 to 80 of about 39,014 (227)

Naringenin alleviates liver fibrosis by triggering autophagy-dependent ferroptosis in hepatic stellate cells

Heliyon
Inhibition of activated hepatic stellate cells (HSCs) is a promising approach for treating liver fibrosis, and the ferroptosis has emerged as a pivotal mechanism to achieve this inhibition.
Ting Yu, Xuejia Lu, Yan Liang, Lin Yang, Yuehan Yin, Hong Chen   +5 more
doaj   +1 more source

Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice[S]

Journal of Lipid Research, 2013
Obesity-associated chronic inflammation contributes to metabolic dysfunction and propagates atherosclerosis. Recent evidence suggests that increased dietary cholesterol exacerbates inflammation in adipose tissue and liver, contributing to the ...
Julia M. Assini, Erin E. Mulvihill, Brian G. Sutherland, Dawn E. Telford, Cynthia G. Sawyez, Sarah L. Felder, Sanjiv Chhoker, Jane Y. Edwards, Robert Gros, Murray W. Huff   +9 more
doaj   +1 more source

Antimicrobial Effect of 7-O-Butylnaringenin, a Novel Flavonoid, and Various Natural Flavonoids against Helicobacter pylori Strains [PDF]

, 2013
: The antimicrobial effect of a novel flavonoid (7-O-butylnaringenin) on Helicobacter pylori 26695, 51, and SS1 strains and its inhibitory effect on the urease activity of the strains were evaluated and compared with those of several natural flavonoids ...
Ahn, Dong, Ahn, Dong, Kim, Kee-Tae, Lee, Jae Hoon, Moon, Sun Hee, Nah, Seung-Yeol, Paik, Hyun-Dong, Park, Yong-Suhn   +7 more
core   +3 more sources

Degradation of pigments in Limnospira platensis extracts

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Limnospira platensis, commonly known as spirulina, holds promise for application as a food ingredient and nutraceutical due to its rich protein and antioxidant content, including chlorophylls, carotenoids and phycocyanin. Despite its potential, the vibrant colour poses a challenge for consumer acceptance, hampering the marketability
Marisa Cardoso, Carla Brazinha, Carla AM Portugal   +2 more
wiley   +1 more source

Naringenin counteracts LPS-induced inflammation and immune deficits in chicken thymus by alleviating mtROS/ferroptosis levels

Poultry Science
: Naringenin is a flavonoid with significant anti-inflammatory and antioxidant properties. Mitochondrial dynamics, the mitochondrial respiratory chain, and mtROS are closely related to each other and regulate various biological processes.
Fei Yu, Xu Shi, Ke Li, Yilin Yin, Shiwen Xu   +4 more
doaj   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Microbial Production of Naringenin

Naringenin is a plant natural compound that belongs to the flavonoid subclass of the polyphenolic compounds. It has several recognized health benefits, namely, antioxidant, anti-inflammatory, anticancer, and antiviral. Given these reported health benefits, an increasing interest in its utilization and incorporation by the pharmaceutical and ...
Gomes, Daniela Filipa Correia, Rodrigues, Joana Lúcia Lima Correia, Rodrigues, L. R.   +2 more
openaire   +2 more sources

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Polyphenol levels in human urine after intake of six different polyphenol-rich beverages [PDF]

, 2005
Dietary polyphenols are suggested to participate in the prevention of CVD and cancer. It is essential for epidemiological studies to be able to compare intake of the main dietary polyphenols in populations.
Adlercreutz, Augustin Scalbert, Booth, Christian Rémésy, Christine Morand, Claudine Manach, Franke, Gonthier, Gutteridge, Hideyuki Ito, Horn-Ross, Hulten, Lampe, Louise Mennen, Manach, Marie-Paule Gonthier, Maskarinec, Nielsen, Shahidi   +18 more
core   +2 more sources

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source