Results 21 to 30 of about 2,438,339 (329)

The adjuvant effect of bacterium-like particles depends on the route of administration

Frontiers in Immunology, 2023
Direct administration of vaccines to mucosal surfaces, such as via oral or nasal vaccination, represents an attractive alternative, or complement, to current parenteral vaccination because it has a potential to induce antigen-specific immunity both at ...
Haruka Sudo, Nagisa Tokunoh, Ayato Tsujii, Sarana Kawashima, Yuta Hayakawa, Hiroki Fukushima, Keita Takahashi, Tetsuo Koshizuka, Naoki Inoue   +8 more
doaj   +1 more source

The Potential of Films as Transmucosal Drug Delivery Systems

Pharmaceutics, 2023
Pharmaceutical films are polymeric formulations used as a delivery platform for administration of small and macromolecular drugs for local or systemic action.
Ana Clara Wada de Carvalho, Natália Floriano Paiva, Isabella Kriunas Demonari, Maíra Peres Ferreira Duarte, Renê Oliveira do Couto, Osvaldo de Freitas, Fabiana Testa Moura de Carvalho Vicentini   +6 more
doaj   +1 more source

Phospholipid Vesicles for Dermal/Transdermal and Nasal Administration of Active Molecules: The Effect of Surfactants and Alcohols on the Fluidity of Their Lipid Bilayers and Penetration Enhancement Properties

Molecules, 2020
This is a comprehensive review on the use of phospholipid nanovesicles for dermal/transdermal and nasal drug administration. Phospholipid-based vesicular carriers have been widely investigated for enhanced drug delivery via dermal/transdermal routes ...
Hiba Natsheh, E. Touítou
semanticscholar   +1 more source

Drug delivery to the brain via the nasal route of administration: exploration of key targets and major consideration factors

Journal of Pharmaceutical Investigation, 2022
Background Cranial nerve-related diseases such as brain tumors, Alzheimer’s disease, and epilepsy are serious diseases that continue to threaten human. Brain-related diseases are increasing worldwide, including in the United States and Korea, and these ...
Seung-Hyun Jeong, J. Jang, Yong-Bok Lee
semanticscholar   +1 more source

Nasal Drug Delivery Systems: An Overview [PDF]

, 2015
Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades ...
Conway, Barbara R., Ghori, Muhammad U., Mahdi, Mohammed H., Smith, Alan M.   +3 more
core   +1 more source

Short Onset and Enhanced Analgesia Following Nasal Administration of Non-Controlled Drugs in Nanovesicular Systems

Pharmaceutics, 2021
Nasal nanovesicular delivery systems (NVS) containing the noncontrolled analgesic drugs Ketoprofen, Butorphanol or Tramadol, incorporated in a phospholipid nanovesicular carrier, were designed and investigated.
Elka Touitou, Hiba Natsheh, Shatha Boukeileh, Rania Awad   +3 more
doaj   +1 more source

Physico-Chemical and In Vitro Characterization of Chitosan-Based Microspheres Intended for Nasal Administration

Pharmaceutics, 2021
The absorption of non-steroidal anti-inflammatory drugs (NSAIDs) through the nasal epithelium offers an innovative opportunity in the field of pain therapy.
Csilla Bartos, Patrícia Varga, Piroska Szabó-Révész, Rita Ambrus   +3 more
doaj   +1 more source

Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats [PDF]

, 2003
The aim of this work was to study in rats the nasal route for the brain delivery of the vasoactive intestinal peptide (VIP) neuropeptide. After evaluating VIP stability in solutions obtained from nasal washes, the effect of formulation parameters (pH 4-9,
Couet, William, Dufès, Christine, Gaillard, Afsaneh, Gaillard, Frédéric, Muller, Jean-Marc, Olivier, Jean-Christophe   +5 more
core   +3 more sources

Spatial Distribution of (R)-salbutamol in Rat Brain Following Nasal and Intravenous Administration Using DESI-MS

Pharmaceutics, 2020
Recent studies have shown that β2-Adrenoreceptor is a regulator of the a-synuclein gene driving risk of Parkinson’s disease. The β2-AR agonist (R)-salbutamol, eutomer of rac-salbutamol, may hold therapeutic potential for Parkinson’s
Rui Zhang, Jie Wu, Siyu Liu, LiangJun Deng, Junhua Hu, Xi Chen, Wen Tan   +6 more
doaj   +1 more source

A case of rhinoscleroma treated with ciprofloxacin [PDF]

, 2001
Respiratory scleroma (often termed \'rhinoscleroma\') is a chronic inflammatory condition in which deforming masses of tissue distend the nasal cavity. Klebsiella rhinoscleromatis is the causative agent of this infection and the Mikulicz cell is specific
Badia, L, Lund, VJ
core   +1 more source