Results 11 to 20 of about 262,065 (292)

Strategies to Enhance Drug Absorption via Nasal and Pulmonary Routes

open access: yesPharmaceutics, 2019
New therapeutic agents such as proteins, peptides, and nucleic acid-based agents are being developed every year, making it vital to find a non-invasive route such as nasal or pulmonary for their administration.
Maliheh Ghadiri   +2 more
doaj   +3 more sources

In Vitro Studies on Nasal Formulations of Nanostructured Lipid Carriers (NLC) and Solid Lipid Nanoparticles (SLN)

open access: yesPharmaceuticals, 2021
The nasal route has been used for many years for the local treatment of nasal diseases. More recently, this route has been gaining momentum, due to the possibility of targeting the central nervous system (CNS) from the nasal cavity, avoiding the blood ...
Cláudia Pina Costa   +6 more
doaj   +1 more source

Hyper-Enriched Anti-RSV Immunoglobulins Nasally Administered: A Promising Approach for Respiratory Syncytial Virus Prophylaxis

open access: yesFrontiers in Immunology, 2021
Respiratory syncytial virus (RSV) is a public health concern that causes acute lower respiratory tract infection. So far, no vaccine candidate under development has reached the market and the only licensed product to prevent RSV infection in at-risk ...
Emilie Jacque   +16 more
doaj   +1 more source

Hyaluronic acid: perspectives in upper aero-digestive tract. A systematic review [PDF]

open access: yes, 2015
Background: To date, topical therapies guarantee a better delivery of high concentrations of pharmacologic agents to the mucosa of the upper aerodigestive tract (UADT).
Baptista, Peter   +7 more
core   +15 more sources

Comparison of Modern In Vitro Permeability Methods with the Aim of Investigation Nasal Dosage Forms

open access: yesPharmaceutics, 2021
Nowadays, the intranasal route has become a reliable alternative route for drug administration to the systemic circulation or central nervous system. However, there are no official in vitro diffusion and dissolution tests especially for the investigation
Csilla Bartos   +4 more
doaj   +1 more source

Preparation, In Vitro and In Vivo Evaluation of Nanoemulsion In Situ Gel for Transnasal Delivery of Traditional Chinese Medicine Volatile Oil from Ligusticum sinense Oliv.cv. Chaxiong

open access: yesMolecules, 2022
Ischemic stroke is a difficult-to-treat brain disease that may be attributed to a limited therapeutic time window and lack of effective clinical drugs. Nasal–brain administration is characterized by low systemic toxicity and is a direct and non-invasive ...
Chunhui Huang   +10 more
doaj   +1 more source

The adjuvant effect of bacterium-like particles depends on the route of administration

open access: yesFrontiers in Immunology, 2023
Direct administration of vaccines to mucosal surfaces, such as via oral or nasal vaccination, represents an attractive alternative, or complement, to current parenteral vaccination because it has a potential to induce antigen-specific immunity both at ...
Haruka Sudo   +8 more
doaj   +1 more source

The Potential of Films as Transmucosal Drug Delivery Systems

open access: yesPharmaceutics, 2023
Pharmaceutical films are polymeric formulations used as a delivery platform for administration of small and macromolecular drugs for local or systemic action.
Ana Clara Wada de Carvalho   +6 more
doaj   +1 more source

Nasal Drug Delivery Systems: An Overview [PDF]

open access: yes, 2015
Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades ...
Conway, Barbara R.   +3 more
core   +1 more source

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