Results 21 to 30 of about 262,065 (292)
Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats [PDF]
, 2003 The aim of this work was to study in rats the nasal route for the brain delivery of the vasoactive intestinal peptide (VIP) neuropeptide. After evaluating VIP stability in solutions obtained from nasal washes, the effect of formulation parameters (pH 4-9,
Couet, William +5 more
core +3 more sources
Pharmaceutics, 2020 Recent studies have shown that β2-Adrenoreceptor is a regulator of the a-synuclein gene driving risk of Parkinson’s disease. The β2-AR agonist (R)-salbutamol, eutomer of rac-salbutamol, may hold therapeutic potential for Parkinson’s
Rui Zhang +6 more
doaj +1 more source
A patient preference study that evaluated fluticasone furoate and mometasone furoate nasal sprays for allergic rhinitis [PDF]
, 2016 Background: Corticosteroid nasal sprays are the mainstay of treatment for allergic rhinitis. These sprays have sensory attributes such as scent and/or odor, taste and aftertaste, and run down the throat and/or the nose, which, when unpleasant, can affect
Bremner, P +6 more
core +2 more sources
Epilepsy & Behavior Reports, 2023 Nasal administration of treatments for neurologic conditions, including rescue therapies to treat seizure clusters among people with epilepsy, represents a meaningful advance in patient care.
Steve Chung +5 more
doaj +1 more source
Current prospects and future challenges for nasal vaccine delivery [PDF]
, 2016 Nasal delivery offers many benefits over traditional approaches to vaccine administration. These include ease of administration without needles that reduces issues associated with needlestick injuries and disposal.
Kett, Vicky, Yusuf, Helmy
core +2 more sources
A Randomized, Double-Blinded, Placebo-Controlled, Cross Over Study Evaluating the Efficacy and Safety of Timolol Ophthalmic Solution as an Acute Treatment of Migraine [PDF]
, 2020 Introduction. Daily oral beta-adrenoreceptor antagonist has been shown to be effective in preventing migraine headaches. Timolol 0.5% ophthalmic solution is a non-selective beta-adrenoreceptor antago- nist, where the primary use is for glaucoma.
Aggarwal, Dipika +10 more
core +2 more sources
Pharmaceuticals, 2021 Cognitive flexibility refers to the ability to modify learned behavior in response to changes in the environment. In laboratory rodents, cognitive flexibility can be assessed in reversal learning, i.e., the change of contingencies, for example in T-maze ...
Ahmet Oguzhan Bicakci +4 more
doaj +1 more source
Acute toxicity of the intranasal administration of Anredera cordifolia extract in Wistar Rats [PDF]
PharmacianaAnredera cordifolia (AC) known as the binahong plant in Indonesia has been commonly used for traditional medicine since the ancients. AC contains secondary metabolites such as flavonoids that have anti-oxidative, anti-inflammatory, anti-mutagenic, and ...
Asti Widuri, Rifki Febriansah
doaj +1 more source
Pharmaceutics, 2021 Recent advances have been reported for needle-free local anesthesia in maxillary teeth by administering a nasal spray of tetracaine (TTC) and oxymetazoline, without causing pain, fear, and stress.
Giovana Maria Fioramonti Calixto +9 more
doaj +1 more source
Neural correlates of emotion processing comparing antidepressants and exogenous oxytocin in postpartum depressed women: An exploratory study [PDF]
, 2019 Despite common use of antidepressants to treat postpartum depression, little is known about the impact of antidepressant use on postpartum brain activity.
Cheng, Hu +2 more
core +3 more sources