Results 31 to 40 of about 49,420 (307)

Safety and efficacy of a propofol and ketamine based procedural sedation protocol in children with cerebral palsy undergoing botulinum toxin A injections. [PDF]

, 2019
Background Pediatric patients with cerebral palsy (CP) often undergo intramuscular botulinum toxin (BoNT‐A) injections. These injections can be painful and may require procedural sedation.
Abu-Sultaneh, Samer, Abulebda, Kamal, Louer, Ryan, Lutfi, Riad, McKinney, Renee C.   +4 more
core   +1 more source

Influence of excipients on spray-dried powders for inhalation [PDF]

, 2014
Two areas attracting considerable attention when developing effective pulmonary drug delivery systems include the improvement of aerosolisation efficiency of the inhaled formulation and the controlled release of drug from the formulation following ...
Adi, Azarmi, Begat, Chan, Chew, Chew, Conti, Corrigan, Coucke, Derom, Edwards, Ely, En-Yu Xu, Farid, Glover, Gray, Griesenbach, Hao-Ying Li, Hooton, Jalalipour, Jing Guo, Kamiya, Kobayashi, Learoyd, Learoyd, Li, Li, Li, Li, Li, Mishra, Momeni, Parsons, Patton, Peter C. Seville, Prakash Rao, Seville, Seville, Sham, Sinn, Sou, Sou, Ståhl, Vergote, Ying Xu, Zeng   +45 more
core   +1 more source

Formulation and kinetic modeling of curcumin loaded intranasal mucoadhesive microemulsion

Journal of Pharmacy and Bioallied Sciences, 2012
It is a challenge to develop the optimum dosage form of poorly water-soluble drugs and to target them due to limited bioavailability, intra and inter subject variability.
B Mikesh Patel, Surjyanarayan Mandal, K S Rajesh   +2 more
doaj   +1 more source

Assay of Desmopressin Acetate in Nasal Spray: Development of Validated Pre Column HPLC-Fluorescence Method [PDF]

Advanced Pharmaceutical Bulletin, 2017
Purpose: Desmopressin acetate (DDAPV), a synthetic analogue of vasopressin, has been recommended to be used in diabetes insipidus, mild forms of hemophilia and Von Willebrand disease.
Neeraj Upmanyu, Pawan Kumar Porwal
doaj   +1 more source

Nano-adjuvanted dry powder vaccine for the mucosal immunization against airways pathogens

Frontiers in Veterinary Science, 2023
Nasal vaccination has been shown to provide optimal protection against respiratory pathogens. However, mucosal vaccination requires the implementation of specific immunization strategies to improve its effectiveness. Nanotechnology appears a key approach
Elena Canelli, Luca Ferrari, Paolo Borghetti, Francesco Candela, Nkemjika Sopuru Abiakam, Annalisa Bianchera, Annalisa Bianchera, Francesca Buttini, Francesca Buttini, Gian Enrico Magi, Fabio Sonvico, Fabio Sonvico, Paolo Martelli, Ruggero Bettini, Ruggero Bettini   +14 more
doaj   +1 more source

Pneumoventricle of Unknown Origin. A Personal Experience and Literature Review of a Clinical Enigma [PDF]

, 2019
Pneumocephalus (PC) is an uncommon and life-threatening neurological condition. Air within the ventricular system of the brain is also known as Pneumoventricle (PV). It requires emergency treatments to prevent catastrophic neurological outcomes.
Armocida, Daniele, Frati, Alessandro, Miscusi, Massimo, Paglia, Francesco, Pesce, Alessandro, Raco, Antonino   +5 more
core   +1 more source

Evaluation of microbiological purity of nasal ointment "Mnemastym"

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
The aim of this work was the determination of microbiological purity of nasal ointment “Mnemastym” with arginine-vasopressin (AVP). Materials and methods.
Al Nukari Abdulkarim, О. S. Koshelev, A. L. Drozdov   +2 more
doaj   +1 more source

Efficacy and safety of two Ayurvedic dosage forms for allergic rhinitis: Study protocol for an open-label randomized controlled trial

Trials, 2020
Background Allergic rhinitis (AR) is an immune response of the nasal mucosa to airborne allergens and involves nasal congestion, watery nasal discharge, itching of the nose, and sneezing.
Jeevani Maheshika Dahanayake, Pathirage Kamal Perera, Priyadarshani Galappaththy, Dulani Samaranayake   +3 more
doaj   +1 more source

Intranasal delivery of Clozapine using nanoemulsion-based in-situ gels: An approach for bioavailability enhancement

Saudi Pharmaceutical Journal, 2021
Limited solubility and hepatic first-pass metabolism are the main causes of low bioavailability of anti-schizophrenic drug, Clozapine (CZP). The objective of the study was to develop and validate nanoemulsion (NE) based in-situ gel of CZP for intranasal ...
Nourhan A. Abdulla, Gehan F. Balata, Hanaa A. El-ghamry, Eman Gomaa   +3 more
doaj   +1 more source

Solid Lipid Nanoparticles Containing Dopamine and Grape Seed Extract: Freeze-Drying with Cryoprotection as a Formulation Strategy to Achieve Nasal Powders

Molecules, 2023
(1) Background: DA-Gelucire® 50/13-based solid lipid nanoparticles (SLNs) administering the neurotransmitter dopamine (DA) and the antioxidant grape-seed-derived proanthocyanidins (grape seed extract, GSE) have been prepared by us in view of a possible ...
Elvira De Giglio, Udo Bakowsky, Konrad Engelhardt, Antonello Caponio, Matteo La Pietra, Stefania Cometa, Stefano Castellani, Lorenzo Guerra, Giuseppe Fracchiolla, Maria Luana Poeta, Rosanna Mallamaci, Rosa Angela Cardone, Stefano Bellucci, Adriana Trapani   +13 more
doaj   +1 more source