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Full Clinical Pathological and Bacteriological Investigation of a Giant Nasal Polyp Associated With the Developing Apex of the Permanent Fourth Premolar (Triadan 108) in a 3-year-old Connemara Filly: A Case Report. [PDF]
Vet Med SciA 3‐year‐old Connemara X filly presented with unilateral nasal discharge and facial swelling. Diagnostic imaging revealed a soft tissue mass with mineralisation and dental pathology (108). Histopathology confirmed a fibro‐inflammatory polyp. This case highlights a rare equine sino‐nasal polyp associated with endodontic disease, demonstrating a ...
Sidwell A +6 more
europepmc +2 more sources
Mediators of Inflammation, 2014 Nasal polyposis is a severe, chronic inflammatory condition of the paranasal sinuses and is frequently associated with asthma and aspirin sensitivity.
R. Pezato +8 more
semanticscholar +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Verekitug, a novel, high‐affinity, fully human monoclonal antibody targeting thymic stromal lymphopoietin receptor (TSLPR), is in development as a potential treatment for severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and chronic obstructive pulmonary disease (COPD).
Dave Singh +9 more
wiley +1 more source
World Allergy Organization Journal, 2019 Background: Eosinophilic inflammation is a major phenotype associated with poorly controlled disease in nasal polyp patients. The difference between systemic and local eosinophilia in relation to disease control is poorly understood.
Kanghua Wang +8 more
doaj +1 more source
The Laryngoscope, 2014 The role of fungi in chronic rhinosinusitis (CRS) is still controversial. The present study was conducted to detect and identify fungal species from the nasal polyp tissues of eosinophilic and noneosinophilic CRS, and to determine the role of fungal ...
M. Hirotsu +5 more
semanticscholar +1 more source
Bone: the final frontier for Staphylococcus aureus penetration in chronic rhinosinusitis [PDF]
, 2013 The superantigenic properties of Staphylococcus aureus have been implicated in increasing the inflammatory process in airway diseases. Local formation of IgE antibodies against staphylococcal enterotoxins by secondary lymphoid tissue in nasal polyps has ...
Bachi, Andre Luis Lacerda +5 more
core +2 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin +6 more
wiley +1 more source
Giant Antrochoanal Polyp-A Rare Presentation [PDF]
Journal of Clinical and Diagnostic Research, 2017 Antrochoanal polyp (ACP), also called as Killian polyp, is an infrequent, benign lesion of maxillary origin in non-atopic patients. The antrochoanal polyp is shaped according to the anatomical constraints of the lateral nasal wall, particularly the ...
Swati Kodur +2 more
doaj +1 more source
Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]
, 2013 Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A +2 more
core +2 more sources
iMetaOmics, EarlyView.Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory condition. Dysbiosis is commonly observed. This study identified distinct sinonasal microbial communities in CRSwNP patients and explored their clinical and pathological associations. Two distinct microbial communities were identified: community type 1 (CT1), dominated by
Bixing Fang +10 more
wiley +1 more source