Results 61 to 70 of about 375,973 (338)

Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease (AERD)

Biomolecules, 2021
Background: Aspirin-exacerbated respiratory disease (AERD) is a syndrome characterised by chronic rhinosinusitis, nasal polyps, asthma and aspirin intolerance. An imbalance of eicosanoid metabolism with anover-production of cysteinyl leukotrienes (CysLTs)
V.S. Priyadharshini, Marcos Alejandro Jiménez-Chobillon, Jos de Graaf, Raúl Porras Gutiérrez de Velasco, Christina Gratziou, Fernando Ramírez-Jiménez, Luis M. Teran   +6 more
doaj   +1 more source

GATA3 Deletion Associated With Juvenile Idiopathic Arthritis: Expanding the Phenotypic Spectrum of Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss, Amanda V. Karam, Julia Shalen, David E. Tunkel, Belina Y. Yi, Kelsey S. Guthrie, Emily M. Kudalkar, Anna E. Patrick, Sonja A. Rasmussen   +8 more
wiley   +1 more source

Association Between the Expression of Cytochrome P450 and Glutathione S-transferase Enzyme and Antrochoanal Polyp Pathogenesis

International Archives of Otorhinolaryngology
Introduction Antrochoanal polyp, which is a kind of smooth-surfaced single nasal polyp, is commonly present in cases of nasal obstruction. The pathogenesis of polyp formation is still unclear, but allergy is supposed to be a cause.
Mehmet Gökhan Demir, Sedat Aydın, Serpil Oguztuzun, Kayhan Basak   +3 more
doaj   +1 more source

Enhanced susceptibility of nasal polyp tissues to avian and human influenza viruses. [PDF]

PLoS ONE, 2010
BACKGROUND: Influenza viruses bind and infect respiratory epithelial cells through sialic acid on cell surface. Differential preference to sialic acid types contributes to host- and tissue-tropism of avian and seasonal influenza viruses.
Ornpreya Suptawiwat, Pongsakorn Tantilipikorn, Chompunuch Boonarkart, Jate Lumyongsatien, Mongkol Uiprasertkul, Pilaipan Puthavathana, Prasert Auewarakul   +6 more
doaj   +1 more source

Cadherin‐26 Facilitates Transepithelial Migration of Eosinophils in Eosinophilic Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by persistent sinonasal inflammation and marked eosinophilic infiltration. Although the relationship between eosinophils and NP formation has been extensively studied, the mechanisms governing eosinophil transepithelial migration into the nasal mucosa ...
Yeong‐In Jo, Jee Won Moon, Joo‐Hoo Park, Hwa Eun Yang, Subin Cho, Hyeongguk Son, Hyun‐Woo Yang, Il‐Ho Park   +7 more
wiley   +1 more source

European Academy of Allergy and Clinical Immunology position paper on endoscopic scoring of nasal polyposis

Allergy. European Journal of Allergy and Clinical Immunology, 2023
Nasal endoscopy is not only used for the diagnosis of chronic rhinosinusitis with nasal polyps (CRSwNP), but also for monitoring the response to therapy playing an important role in both daily practice and research.
P. Gevaert, Jarno De Craemer, C. Bachert, Manon Blauwblomme, A. Chaker, C. Cingi, P. Hellings, C. Hopkins, V. Hox, W. Fokkens, L. Klimek, V. Lund, R. Mösges, J. Mullol, O. Pfaar, G. Scadding, P. Tomazic, T. Van Zele, S. Vlaminck, M. Wagenmann, S. Toppila-Salmi, I. Alobid   +21 more
semanticscholar   +1 more source

Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis [PDF]

, 2015
BACKGROUND: This review is one of a suite of six Cochrane reviews looking at the primary medical management options for patients with chronic rhinosinusitis.Chronic rhinosinusitis is a common condition involving inflammation of the lining of the nose and
Cho, DeMarcantonio, Drunen, Ebbens, Ebbens, Egger, Fokkens, Gliklich, Hastan, Kern, Keswani, Larsen, Martinez-Devesa, Mygind, Ragab, Ragab, Tan, Tomassen, Zhang, Zhang   +19 more
core   +1 more source

Machine Learning‐Enhanced Clinical Decision Support for Diagnosing Sinusitis With Nasal Endoscopy

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinusitis is a prevalent disease for which nasal endoscopy (NE) is an optimal diagnostic modality. However, NE accuracy is limited by inter‐operator variability in landmark identification and localization of mucus that is necessary for sinusitis diagnosis. We sought to develop a novel multi‐class machine learning (ML) framework that
Dipesh Gyawali, Thomas Mundy, Majid Hosseini, Morteza Bodaghi, Akio Fujiwara, Sejal Shyam Bhatia, Kayla Baker, Elena Bartolone, Dhara Patel, Henry Chu, Raju Gottumukkala, Jonathan Bidwell, Edward D. McCoul   +12 more
wiley   +1 more source

Nasal polyps in children

Turkish Archives of Otorhinolaryngology, 2007
Objectives: Nasal polyps in the children are uncommon and its etiology is unclear. The purpose of this study is evaluation the alternatives of treatment, histopathological and clinical features of nasal polyposis which in pediatric population, in the ...
Turgut Karlıdağ, Erol Keleş, Cengiz Alpay, Şinasi Yalçın, Ayça Tazegül   +4 more
doaj   +1 more source

Epithelium and stroma from nasal polyp mucosa exhibits inverse expression of TGF- beta(1) as compared with healthy nasal mucosa [PDF]

, 2013
Objective: To evaluate TGF-beta(1) expression in polypoid mucosa (epithelium and stroma) of patients with chronic rhinosinusitis with nasal polyposis (CRSwNP).Methods: Cross-sectional study with two groups: 17 patients with nasal polyposis and 11 ...
Alves, Maria Teresa S., Bachert, Claus, Balsalobre, Leonardo, Perez-Novo, Claudina, Pezato, Rogerio, Santos, Rodrigo P., Weckx, Luc L. M.   +6 more
core   +2 more sources