Results 1 to 10 of about 1,421,573 (256)

TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

Nature Communications, 2023
The molecular mechanisms determining the response to radiotherapy remain incompletely understood. Here, the authors demonstrate that the E3 ubiquitin ligase and intracellular Fc receptor, TRIM21, impairs CD8+ T cell responses in nasopharyngeal carcinoma ...
Jun-Yan Li, Yin Zhao, Sha Gong, Miao-Miao Wang, Xu Liu, Qing-Mei He, Ying-Qin Li, Sheng-Yan Huang, Han Qiao, Xi-Rong Tan, Ming-Liang Ye, Xun-Hua Zhu, Shi-Wei He, Qian Li, Ye-Lin Liang, Kai-Lin Chen, Sai-Wei Huang, Qing-Jie Li, Jun Ma, Na Liu   +19 more
doaj   +2 more sources

Nasopharyngeal carcinoma in children [PDF]

Cancer, 1976
Ten children with lymphoepithelioma of the nasopharynx were reviewed. Six had regional spread at presentation and four developed distant metastases. Seven patients are alive, six free of disease. The 5-year survival rate was 62.5% of this series. Five patients presented later with endocrine abnormalities probably related to the radiotherapy; these ...
C. Hernández Fernández, Ayten Cangır, Naguib A. Samaan, Roberto Rivera   +3 more
openalex   +4 more sources

Nasopharyngeal carcinoma

The Lancet, 2019
Nasopharyngeal carcinoma is characterised by distinct geographical distribution and is particularly prevalent in east and southeast Asia. Epidemiological trends in the past decade have shown that its incidence has declined gradually but progressively, and mortality has been reduced substantially.
Yupei Chen, A. Chan, Q. Le, P. Blanchard, Ying Sun, Jun Ma   +5 more
semanticscholar   +6 more sources

Prognostic Significance of Circulating Immune Subset Counts in Nasopharyngeal Carcinoma [PDF]

ImmunoTargets and Therapy
Honghui Xie,1– 3,* Lin Zhang,1,3,4,* Lizhi Chen,5,* Wenchao Zhou,1,6 Lijuan Zhang,1,3 Yong Su,1– 3 Bocheng Li,1,6 Peng Ding,1,6 Yun Xiao,1– 3 Tianzhu Lu,1,2,4,7 Xiaochang Gong,1,2,4,7 Jingao Li1,2,4,7 1NHC Key Laboratory of ...
Xie H, Zhang L, Chen L, Zhou W, Zhang L, Su Y, Li B, Ding P, Xiao Y, Lu T, Gong X, Li J   +11 more
doaj   +2 more sources

Nasopharyngeal carcinoma [PDF]

The Lancet, 2005
Incidence of nasopharyngeal carcinoma has remained high in endemic regions. Diagnosing the disease in the early stages requires a high index of clinical acumen and, although most cross-sectional imaging investigations show the tumour with precision, confirmation is dependent on histology.
Wei, WI, Sham, JST
openaire   +7 more sources

Clinical advances in nasopharyngeal carcinoma surgery and a video demonstration

Visualized Cancer Medicine, 2021
Nasopharyngeal carcinoma (NPC) is highly radiosensitive, and radiotherapy is recommended for newly diagnosed NPC. Because of the poor visual surgical field, narrow operating space, difficulty protecting the internal carotid artery (ICA) and poor wound ...
Ding Xi, Liu You-Ping, Hua Yi-Jun, Zou Xiong, Wang Zhi-Qiang, Xie Yu-Long, Chen Ming-Yuan   +6 more
doaj   +1 more source

Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction

Nature Communications, 2023
Despite the intense CD8+ T-cell infiltration in the tumor microenvironment of nasopharyngeal carcinoma, anti-PD-1 immunotherapy shows an unsatisfactory response rate in clinical trials, hindered by immunosuppressive signals.
Lanqi Gong, Jie Luo, Yu Zhang, Yu-Ma Yang, Shan-Shan Li, Xiaona Fang, Baifeng Zhang, Jiao-Ren Huang, Larry Ka-Yue Chow, D. Chung, Jin-Lin Huang, Cuicui Huang, Qin Liu, Lu Bai, Yuen Chak Tiu, Pingan Wu, Yan Wang, G. Tsao, D. Kwong, A. Lee, W. Dai, X. Guan   +21 more
semanticscholar   +1 more source

The Chinese Society of Clinical Oncology (CSCO) clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma

Cancer Communications, 2021
Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor originating in the nasopharynx and has a high incidence in Southeast Asia and North Africa.
L. Tang, Yupei Chen, Chuanben Chen, Ming-Yuan Chen, N. Chen, Xiaozhong Chen, Xiao-jing Du, W. Fang, M. Feng, Jin Gao, F. Han, Xia He, Chaosu Hu, Denghua Hu, G. Hu, Hao Jiang, Wei Jiang, F. Jin, J. Lang, Jin-Gao Li, Shaojun Lin, Xu Liu, Qiuhua Liu, Lin Ma, H. Mai, Jiyong Qin, Liangfang Shen, Ying Sun, Pei-guo Wang, Ren-Sheng Wang, Ruo-Zheng Wang, Xiaoshen Wang, Ying Wang, Huifang Wu, Yun-Fei Xia, S. Xiao, Kun-yu Yang, J. Yi, Xiao-dong Zhu, Jun Ma   +39 more
semanticscholar   +1 more source

EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma

Cell Death and Differentiation, 2022
Epstein–Barr virus (EBV) was the first oncogenic virus identified in humans. It is primarily associated with multiple lymphoid and epithelial cancers, including nasopharyngeal carcinoma (NPC).
Li Yuan, Shibing Li, Qiu-Yan Chen, Tian-Liang Xia, D. Luo, Liangji Li, Sai-Lan Liu, Shan-Shan Guo, Li-Ting Liu, Chaochao Du, G. Jia, Xiaoyun Li, Zi-Jian Lu, Zhenchong Yang, Huanliang Liu, Haiqiang Mai, Linquan Tang   +16 more
semanticscholar   +1 more source

Nasopharyngeal carcinoma in situ in nasopharyngeal carcinoma. [PDF]

Journal of Clinical Pathology, 1992
AIMS: To assess the presence of carcinoma in situ (CIS) in patients with nasopharyngeal carcinoma (NPC) and to see if the number of biopsy sites facilitates detection of CIS. METHODS: Formalin fixed, paraffin wax embedded biopsy specimens (n = 285) from 187 patients with NPC in 1987 were studied for the presence of CIS as well as for the histological ...
Chan, CW, Choy, D, Sham, JST, Dickens, P, Nicholls, JM   +4 more
openaire   +4 more sources