Results 1 to 10 of about 1,479,789 (367)
Nature Communications, 2023 The molecular mechanisms determining the response to radiotherapy remain incompletely understood. Here, the authors demonstrate that the E3 ubiquitin ligase and intracellular Fc receptor, TRIM21, impairs CD8+ T cell responses in nasopharyngeal carcinoma ...
Jun-Yan Li +19 more
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Nasopharyngeal carcinoma in children [PDF]
Cancer, 1976 Ten children with lymphoepithelioma of the nasopharynx were reviewed. Six had regional spread at presentation and four developed distant metastases. Seven patients are alive, six free of disease. The 5-year survival rate was 62.5% of this series. Five patients presented later with endocrine abnormalities probably related to the radiotherapy; these ...
C. Hernández Fernández +3 more
openalex +4 more sources
Predictive value of nasopharyngeal microbiota for necrosis after re-irradiation in recurrent nasopharyngeal carcinoma [PDF]
BMC CancerBackground Post-radiation nasopharyngeal necrosis (PRNN) is a severe complication following re-irradiation in patients with recurrent nasopharyngeal carcinoma (NPC).
Kai Wen +10 more
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The Lancet, 2019 Nasopharyngeal carcinoma is characterised by distinct geographical distribution and is particularly prevalent in east and southeast Asia. Epidemiological trends in the past decade have shown that its incidence has declined gradually but progressively, and mortality has been reduced substantially.
Yupei Chen +5 more
semanticscholar +6 more sources
Prognostic Significance of Circulating Immune Subset Counts in Nasopharyngeal Carcinoma [PDF]
ImmunoTargets and TherapyHonghui Xie,1– 3,* Lin Zhang,1,3,4,* Lizhi Chen,5,* Wenchao Zhou,1,6 Lijuan Zhang,1,3 Yong Su,1– 3 Bocheng Li,1,6 Peng Ding,1,6 Yun Xiao,1– 3 Tianzhu Lu,1,2,4,7 Xiaochang Gong,1,2,4,7 Jingao Li1,2,4,7 1NHC Key Laboratory of ...
Xie H +11 more
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Nasopharyngeal carcinoma [PDF]
The Lancet, 2005 Incidence of nasopharyngeal carcinoma has remained high in endemic regions. Diagnosing the disease in the early stages requires a high index of clinical acumen and, although most cross-sectional imaging investigations show the tumour with precision, confirmation is dependent on histology.
Wei, WI, Sham, JST
openaire +7 more sources
Clinical advances in nasopharyngeal carcinoma surgery and a video demonstration
Visualized Cancer Medicine, 2021 Nasopharyngeal carcinoma (NPC) is highly radiosensitive, and radiotherapy is recommended for newly diagnosed NPC. Because of the poor visual surgical field, narrow operating space, difficulty protecting the internal carotid artery (ICA) and poor wound ...
Ding Xi +6 more
doaj +1 more source
The role of Epstein–Barr virus in nasopharyngeal carcinoma
Frontiers in Microbiology, 2023 Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC incidences displayed predominance in certain ethnic groups and endemic regions.
Zhijie Su, P. Siak, C. Leong, S. Cheah
semanticscholar +1 more source
Nature Communications, 2023 Despite the intense CD8+ T-cell infiltration in the tumor microenvironment of nasopharyngeal carcinoma, anti-PD-1 immunotherapy shows an unsatisfactory response rate in clinical trials, hindered by immunosuppressive signals.
Lanqi Gong +21 more
semanticscholar +1 more source
Current Treatment Options in Oncology, 2023 Nasopharyngeal carcinoma (NPC) is distinct in its anatomic location and biology from other epithelial head and neck cancer (HNC). There are 3 WHO subtypes, which considers the presence of Epstein-Barr virus (EBV) and other histopathology features ...
J. J. Juarez-Vignon Whaley +7 more
semanticscholar +1 more source