Results 11 to 20 of about 30,077 (242)

Evaluation of intrafraction couch shifts for proton treatment delivery in head‐and‐neck cancer patients: Toward optimal imaging frequency

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Treatment planning for head‐and‐neck (H&N) cancer, in particular oropharynx, nasopharynx, and paranasal sinus cases, at our center requires noncoplanar proton beams due to the complexity of the anatomy and target location. Targeting accuracy for all beams is carefully evaluated by using image guidance before delivering proton beam ...
Nrusingh C. Biswal   +5 more
wiley   +1 more source

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

open access: yesCancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022
Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem   +6 more
wiley   +1 more source

Advances in exosome biomarkers for cervical cancer

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4966-4978, December 2022., 2022
Cancer‐derived exosomes may promote CC metastasis by boosting cellular epithelial‐mesenchymal transformation (EMT), controlling the proliferation, invasion, or migration of cancer cells, as well as influencing immune escape and aiding angiogenesis.
Zihan Ran   +5 more
wiley   +1 more source

Spatial heterogeneity of immune infiltration predicts the prognosis of nasopharyngeal carcinoma patients

open access: yesOncoImmunology, 2021
Spatial information on the tumor immune microenvironment is of clinical relevance. Here, we aimed to quantify the spatial heterogeneity of lymphocytes and cancer cells and evaluated its prognostic value in patients with nasopharyngeal carcinoma (NPC ...
Ya-Qin Wang   +14 more
doaj   +1 more source

Risk of subsequent primary lymphoma in a cohort of 69,460 five‐year survivors of childhood and adolescent cancer in Europe: The PanCareSurFup study

open access: yesCancer, Volume 129, Issue 3, Page 426-440, 1 February 2023., 2023
Abstract Background Survivors of Hodgkin lymphoma (HL) are at risk of developing non‐Hodgkin lymphoma (NHL) after treatment; however, the risks of developing subsequent primary lymphomas (SPLs), including HL and NHL, after different types of childhood cancer are unknown.
Isabelle M. Dudley   +38 more
wiley   +1 more source

Minimally invasive surgery alone compared with intensity-modulated radiotherapy for primary stage I nasopharyngeal carcinoma

open access: yesCancer Communications, 2019
Background The National Comprehensive Cancer Network guidelines recommend intensity-modulated radiotherapy (IMRT) as the primary curative treatment for newly diagnosed nasopharyngeal carcinoma (NPC), but the radiation-related complications and relatively
You-Ping Liu   +19 more
doaj   +1 more source

Adding Concurrent Chemotherapy Significantly Improves the Survival of Stage II-IVb Nasopharyngeal Carcinoma Patients Treated With Concurrent Anti-EGFR Agents

open access: yesFrontiers in Oncology, 2021
ObjectiveAnti-EGFR Targeted agents were found to be capable of modulating the antitumor immunity in head and neck cancer and become more and more frequently used in the treatment of nasopharyngeal carcinoma(NPC).
Zi-Kun Yu   +11 more
doaj   +1 more source

Limited recurrence distance of glioblastoma under modern radiotherapy era

open access: yesBMC Cancer, 2021
Background The optimal treatment volume for Glioblastoma multiforme (GBM) is still a subject of debate worldwide. The current study was aimed to determine the distances between recurring tumors and the edge of primary lesions, and thereby provide ...
Ziwei Tu   +5 more
doaj   +1 more source

Empirical comparison of routinely collected electronic health record data for head and neck cancer‐specific survival in machine‐learnt prognostic models

open access: yesHead &Neck, Volume 45, Issue 2, Page 365-379, February 2023., 2023
Abstract Background Knowledge of the prognostic factors and performance of machine learning predictive models for 2‐year cancer‐specific survival (CSS) is limited in the head and neck cancer (HNC) population. Methods Data from our facilities' oncology information system (OIS) collected for routine practice (OIS dataset, n = 430 patients) and research ...
Damian P. Kotevski   +3 more
wiley   +1 more source

TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

open access: yesNature Communications, 2023
The molecular mechanisms determining the response to radiotherapy remain incompletely understood. Here, the authors demonstrate that the E3 ubiquitin ligase and intracellular Fc receptor, TRIM21, impairs CD8+ T cell responses in nasopharyngeal carcinoma ...
Jun-Yan Li   +19 more
doaj   +1 more source

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