Results 21 to 30 of about 30,077 (242)

The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
Background Distant metastasis is the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC). Although several biomarkers correlate with metastasis and prognosis, the molecular mechanisms of NPC development and progression remain
Wen-Ze Qiu   +13 more
doaj   +1 more source

Fully Automatic Segmentation of Gross Target Volume and Organs-at-Risk for Radiotherapy Planning of Nasopharyngeal Carcinoma [PDF]

open access: yesarXiv, 2023
Target segmentation in CT images of Head&Neck (H&N) region is challenging due to low contrast between adjacent soft tissue. The SegRap 2023 challenge has been focused on benchmarking the segmentation algorithms of Nasopharyngeal Carcinoma (NPC) which would be employed as auto-contouring tools for radiation treatment planning purposes.
arxiv  

Stratification of Candidates for Induction Chemotherapy in Stage III-IV Nasopharyngeal Carcinoma: A Large Cohort Study Based on a Comprehensive Prognostic Model

open access: yesFrontiers in Oncology, 2020
Objective: To establish a prognostic index (PI) for patients with stage III-IV nasopharyngeal carcinoma (NPC) patients to personalize recommendations for induction chemotherapy (IC) before intensity-modulated radiotherapy (IMRT).Patients and Methods ...
Xue-Song Sun   +14 more
doaj   +1 more source

Intensive Local Radiotherapy Is Associated With Better Local Control and Prolonged Survival in Bone-Metastatic Nasopharyngeal Carcinoma Patients

open access: yesFrontiers in Oncology, 2020
Objective: To compare the survival outcomes brought by different radiation dose schedules to bone lesions and different chemotherapy regimens in bone metastatic nasopharyngeal carcinoma (NPC).Background: The current treatment strategy for bone metastatic
Xiao-Yun Li   +27 more
doaj   +1 more source

MACC1 Is Associated With Epithelial–Mesenchymal Transition and Can Predict Poor Prognosis in Nasopharyngeal Carcinoma

open access: yesFrontiers in Oncology, 2021
BackgroundGiven the reported correlation between the oncogene metastasis-associated in colon cancer 1 (MACC1) and nasopharyngeal carcinoma (NPC), as well as between MACC1 and epithelial–mesenchymal transition (EMT), we speculated that EMT is a likely ...
Hao Cheng   +5 more
doaj   +1 more source

Network strategies to study Epstein-Barr virus associated carcinomas and potential etiological mechanisms for oncogenesis [PDF]

open access: yesarXiv, 2022
Diseased conditions are a consequence of some abnormality that are associated with clinical conditions in numerous cells and tissues affecting various organs. The common role of EBV (Epstein-Barr virus) in causing infectious mononucleosis (IM) affecting B-cells and epithelial cells and the development of EBV-associated cancers has been an area of ...
arxiv  

Exposures to pesticides and risk of cancer: Evaluation of recent epidemiological evidence in humans and paths forward

open access: yesInternational Journal of Cancer, Volume 152, Issue 5, Page 879-912, 1 March 2023., 2023
Abstract Knowledge of the role in cancer etiology of environmental exposures as pesticides is a prerequisite for primary prevention. We review 63 epidemiological studies on exposure to pesticides and cancer risk in humans published from 2017 to 2021, with emphasis on new findings, methodological approaches, and gaps in the existing literature.
Haleigh Cavalier   +2 more
wiley   +1 more source

SECP-Net: SE-Connection Pyramid Network of Organ At Risk Segmentation for Nasopharyngeal Carcinoma [PDF]

open access: yesarXiv, 2021
Nasopharyngeal carcinoma (NPC) is a kind of malignant tumor. Accurate and automatic segmentation of organs at risk (OAR) of computed tomography (CT) images is clinically significant. In recent years, deep learning models represented by U-Net have been widely applied in medical image segmentation tasks, which can help doctors with reduction of workload ...
arxiv  

Nomogram Predicting the Benefits of Adding Concurrent Chemotherapy to Intensity-Modulated Radiotherapy After Induction Chemotherapy in Stages II–IVb Nasopharyngeal Carcinoma

open access: yesFrontiers in Oncology, 2020
BackgroundTo compare the efficacy of induction chemotherapy plus concurrent chemoradiotherapy (IC+CCRT) versus induction chemotherapy plus radiotherapy (IC+RT) in patients with locoregionally advanced nasopharyngeal carcinoma (NPC).Patients and ...
Sai-Lan Liu   +16 more
doaj   +1 more source

Weighted Concordance Index Loss-based Multimodal Survival Modeling for Radiation Encephalopathy Assessment in Nasopharyngeal Carcinoma Radiotherapy [PDF]

open access: yesarXiv, 2022
Radiation encephalopathy (REP) is the most common complication for nasopharyngeal carcinoma (NPC) radiotherapy. It is highly desirable to assist clinicians in optimizing the NPC radiotherapy regimen to reduce radiotherapy-induced temporal lobe injury (RTLI) according to the probability of REP onset.
arxiv  

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