Results 51 to 60 of about 1,479,789 (367)

Gaps in Treatment and Surveillance: Head and Neck Cancer Care in a Safety-Net Hospital. [PDF]

open access: yes, 2020
Objective:Treatment delays and suboptimal adherence to posttreatment surveillance may adversely affect head and neck cancer (HNC) outcomes. Such challenges can be exacerbated in safety-net settings that struggle with limited resources and serve a ...
Brodie, Shauna   +7 more
core   +1 more source

The Prognostic Role of Plasma Epstein-Barr Virus DNA Levels in the Middle of Intensity Modulated Radiation Therapy to Guide Cisplatin Dose Recommendation in Concurrent Chemoradiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma: A Large Cohort Study

open access: yesAdvances in Radiation Oncology, 2022
Purpose: Our purpose was to investigate the prognostic role of plasma Epstein-Barr virus (EBV) DNA levels in the middle of intensity modulated radiation therapy (IMRT).
Zhen-Chong Yang, MD   +7 more
doaj   +1 more source

Exosomes in Nasopharyngeal Carcinoma [PDF]

open access: yesJournal of Cancer, 2018
Exosomes are nanosized (30-100nm) membrane microvesicles secreted through a complex cellular process. Exosomes contain a variety of bioactive molecules, such as proteins, microRNAs(miRNAs or miRs) and long non-coding RNAs (lncRNAs), playing an important role in the cell-to-cell substance transportation and signal transduction.
Linda Oyang   +11 more
openaire   +2 more sources

Targeting Epstein-Barr Virus in Nasopharyngeal Carcinoma

open access: yesFrontiers in Oncology, 2020
Nasopharyngeal carcinoma (NPC) is consistently associated with Epstein-Barr virus (EBV) infection in regions in which it is endemic, including Southern China and Southeast Asia. The high mortality rates of NPC patients with advanced and recurrent disease
P. Hau   +6 more
semanticscholar   +1 more source

Nasopharyngeal Melanoma [PDF]

open access: yes, 2018
Mucosal nasopharyngeal melanoma is a rare head and neck melanoma. Prognosis is poor (5-year overall survival rate of 10–30%) with high rates of metastases and local recurrence. Head and neck mucosal melanoma represents 0.8–3.7% of all melanomas and 0.03%
Calvieri, Stefano   +4 more
core   +1 more source

Paclitaxel liposome, cisplatin and 5-fluorouracil-based induction chemotherapy followed by de-escalated intensity-modulated radiotherapy with concurrent cisplatin in stage IVA–IVB childhood nasopharyngeal carcinoma in endemic area: a phase II, single-arm trialResearch in context

open access: yesThe Lancet Regional Health. Western Pacific, 2023
Summary: Background: Previous studies demonstrated that induction chemotherapy (IC) followed by de-escalated chemoradiotherapy adapted to tumor response was effective in treating childhood nasopharyngeal carcinoma (NPC), but the toxicity profile of this
Dong-Hua Luo   +16 more
doaj   +1 more source

Advances in targeted therapy mainly based on signal pathways for nasopharyngeal carcinoma

open access: yesSignal Transduction and Targeted Therapy, 2020
Nasopharyngeal carcinoma (NPC) is a malignant epithelial carcinoma of the head and neck region which mainly distributes in southern China and Southeast Asia and has a crucial association with the Epstein–Barr virus.
Yuanbo Kang   +8 more
semanticscholar   +1 more source

Extra-telomeric functions of telomerase in the pathogenesis of Epstein-Barr virus-driven B-cell malignancies and potential therapeutic implications [PDF]

open access: yes, 2018
The Epstein-Barr virus (EBV) is a ubiquitous human \u3b3-herpesvirus causally linked to a broad spectrum of both lymphoid and epithelial malignancies.
Celeghin, Andrea   +4 more
core   +1 more source

Stratification of Candidates for Induction Chemotherapy in Stage III-IV Nasopharyngeal Carcinoma: A Large Cohort Study Based on a Comprehensive Prognostic Model

open access: yesFrontiers in Oncology, 2020
Objective: To establish a prognostic index (PI) for patients with stage III-IV nasopharyngeal carcinoma (NPC) patients to personalize recommendations for induction chemotherapy (IC) before intensity-modulated radiotherapy (IMRT).Patients and Methods ...
Xue-Song Sun   +14 more
doaj   +1 more source

Intensive Local Radiotherapy Is Associated With Better Local Control and Prolonged Survival in Bone-Metastatic Nasopharyngeal Carcinoma Patients

open access: yesFrontiers in Oncology, 2020
Objective: To compare the survival outcomes brought by different radiation dose schedules to bone lesions and different chemotherapy regimens in bone metastatic nasopharyngeal carcinoma (NPC).Background: The current treatment strategy for bone metastatic
Xiao-Yun Li   +27 more
doaj   +1 more source

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