Results 51 to 60 of about 1,463,832 (396)
Extra-telomeric functions of telomerase in the pathogenesis of Epstein-Barr virus-driven B-cell malignancies and potential therapeutic implications [PDF]
, 2018 The Epstein-Barr virus (EBV) is a ubiquitous human \u3b3-herpesvirus causally linked to a broad spectrum of both lymphoid and epithelial malignancies.
Celeghin, Andrea +4 more
core +1 more source
Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma.
New England Journal of Medicine, 2019 BACKGROUND Platinum-based concurrent chemoradiotherapy is the standard of care for patients with locoregionally advanced nasopharyngeal carcinoma. Additional gemcitabine and cisplatin induction chemotherapy has shown promising efficacy in phase 2 trials.
Y. Zhang +46 more
semanticscholar +1 more source
Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]
, 2016 The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin +2 more
core +2 more sources
Frontiers in Oncology, 2020 Objective: To establish a prognostic index (PI) for patients with stage III-IV nasopharyngeal carcinoma (NPC) patients to personalize recommendations for induction chemotherapy (IC) before intensity-modulated radiotherapy (IMRT).Patients and Methods ...
Xue-Song Sun +14 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundGiven the reported correlation between the oncogene metastasis-associated in colon cancer 1 (MACC1) and nasopharyngeal carcinoma (NPC), as well as between MACC1 and epithelial–mesenchymal transition (EMT), we speculated that EMT is a likely ...
Hao Cheng +5 more
doaj +1 more source
Cancer, 2020 The current study was performed to investigate whether circulating cell‐free Epstein‐Barr virus DNA (cfEBV DNA) would be useful for posttreatment surveillance in patients with nasopharyngeal carcinoma (NPC).
Fo-Ping Chen +12 more
semanticscholar +1 more source
Measurement of Epstein-Barr virus DNA load using a novel quantification standard containing two EBV DNA targets and SYBR Green I dye [PDF]
, 2016 BACKGROUND Reactivation of Epstein-Barr virus (EBV) infection may cause serious, life-threatening complications in immunocompromised individuals. EBV DNA is often detected in EBV-associated disease states, with viral load believed to be a reflection of ...
Ausimmune Investigator Group (AIG) +6 more
core +1 more source
Frontiers in Oncology, 2020 Objective: To compare the survival outcomes brought by different radiation dose schedules to bone lesions and different chemotherapy regimens in bone metastatic nasopharyngeal carcinoma (NPC).Background: The current treatment strategy for bone metastatic
Xiao-Yun Li +27 more
doaj +1 more source
Frontiers in Oncology, 2020 BackgroundTo compare the efficacy of induction chemotherapy plus concurrent chemoradiotherapy (IC+CCRT) versus induction chemotherapy plus radiotherapy (IC+RT) in patients with locoregionally advanced nasopharyngeal carcinoma (NPC).Patients and ...
Sai-Lan Liu +16 more
doaj +1 more source
Development of a Nomogram Model for Treatment of Nonmetastatic Nasopharyngeal Carcinoma
JAMA Network Open, 2020 Key Points Question Could a prognostic nomogram that integrates the TNM staging system with other critical variables accurately predict overall survival and guide treatment in patients with nonmetastatic nasopharyngeal carcinoma?
Lu-Lu Zhang +7 more
semanticscholar +1 more source