Results 71 to 80 of about 2,764,193 (353)

Public health and the economy could be served by reallocating medical expenditures to social programs. [PDF]

, 2017
As much as 30% of US health care spending in the United States does not improve individual or population health. To a large extent this excess spending results from prices that are too high and from administrative waste.
Fielding, Jonathan E, Tran, Linda Diem, Zimmerman, Frederick J   +2 more
core   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

“When he is around, I’ll take the PrEP, but when he is not, I will not take PrEP”: key influences on PrEP use decisions among women attending family planning clinics in Kenya

Frontiers in Medicine
BackgroundWomen of childbearing age in sub-Saharan Africa (SSA) face a disproportionately high risk of HIV acquisition. Although oral PrEP has been universally scaled up for individuals at significant risk of HIV, its uptake and sustained use remain ...
Vallery Ogello, Kristin Beima-Sofie, Sandra Urusaro, Mercy Awuor, Annabell Dollah, Winnie Atieno, Cynthia Wandera, Daniel Matemo, Jennifer F. Morton, Kenneth Ngure, Kenneth Ngure, John Kinuthia, John Kinuthia, Kenneth K. Mugwanya, Kenneth K. Mugwanya   +14 more
doaj   +1 more source

Disparities in oral healthcare utilization among diabetic patients in Indonesia [PDF]

Journal of Oral Health and Oral Epidemiology
Background: Indonesia’s National Health Insurance (NHI) system aims to ensure equitable healthcare access; however, significant oral health disparities persist among individuals with diabetes, a group vulnerable to systemic and oral health challenges ...
Riza Fatma Arifa, Marya Yenita Sitohang, Wisnu Fadila   +2 more
doaj   +1 more source

Health Care for Veterans: Answers to Frequently Asked Questions [PDF]

, 2015
The Veterans Health Administration (VHA), within the Department of Veterans Affairs (VA), operates the nation’s largest integrated direct health care delivery system, provides care to approximately 6.6 million unique veteran patients, and employs more ...
Panangala, Sidath Viranga
core   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

First Nations Child and Family Services and Indigenous Knowledge as a Framework for Research, Policy and Practice [PDF]

, 2002
This paper provides an overview of the exciting national developments in First Nations child and family service delivery in Canada with a focus on progressive research, policy and practice.
Bennett, Marlyn, Blackstock, Cindy
core   +1 more source

Assessing the impact of the introduction of the World Health Organization growth standards and weight-for-height z-score criterion on the response to treatment of severe acute malnutrition in children: Secondary data analysis [PDF]

, 2009
OBJECTIVE: The objective of our study was to assess the impact of adopting the World Health Organization growth standards and weight-for-height z-score criterion on the response to treatment of severe acute malnutrition in children compared with the use ...
Grais, R, Isanaka, S, Shepherd, S, Villamor, E   +3 more
core   +2 more sources