Results 81 to 90 of about 2,764,193 (353)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Creating and Managing Change Through Comprehensive School Health Programs [PDF]

, 1999
In 1994, Public Education Network (PEN) entered into a cooperative agreement with the Centers for Disease Control and Prevention, Division of Adolescent and School Health (CDC/DASH) to integrate comprehensive school health programs (CSHP) into a larger ...

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Renewal of the National Cervical Screening Program: health professionals’ knowledge about screening of specific populations in NSW, Australia [PDF]

, 2021
Sally Sweeney, Yan Cheng, Jessica R. Botfield, Deborah Bateson   +3 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Digital communication between mothers and community health workers to support neonatal health (CHV-NEO): study protocol for a randomized controlled trial

Trials
Background Provision of essential newborn care at home, rapid identification of illness, and care-seeking by caregivers can prevent neonatal mortality.
Keshet Ronen, Lincoln C. Pothan, Violet Apondi, Felix A. Otieno, Daniel Mwakanema, Felix O. Otieno, Lusi Osborn, Julia C. Dettinger, Priyanka Shrestha, Helena Manguerra, Ferdinand Mukumbang, Millicent Masinde, Evelyn Waweru, Mercy Amulele, Christine Were, Beatrice Wasunna, Grace John-Stewart, Bryan Weiner, Arianna Rubin Means, Barbra A. Richardson, Anna B. Hedstrom, Jennifer A. Unger, John Kinuthia   +22 more
doaj   +1 more source

Attitudes toward a future norovirus vaccine among members of an integrated healthcare delivery system in Portland, Oregon, 2016-2017

Human Vaccines & Immunotherapeutics
With recent advances in U.S. clinical trials for norovirus vaccines, it is an opportune time to examine what is known about the public receptivity to this novel vaccine. From October 2016–September 2017, we surveyed Kaiser Permanente Northwest members in
Holly C. Groom, Mark Schmidt, Laura E. Calderwood, Sara A. Mirza, Claire Mattison, Suzanne Salas, Judy Donald, Allison L. Naleway   +7 more
doaj   +1 more source

The importance of wellness among users of complementary and alternative medicine: findings from the 2007 National Health Interview Survey. [PDF]

, 2015
BackgroundThis study developed and tested a sociobehavioral wellness model of complementary and alternative medicine (CAM) to differentiate predisposing factors, enabling resources, need, and personal health practices according to use for wellness, for ...
Rainisch, Bethany Wexler, Upchurch, Dawn M   +1 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Avaliação do Programa Mais Médicos: relato de experiência

Saúde em Debate, 2019
RESUMO O acesso à saúde de forma universal e equitativa está preconizado na Constituição Federal de 1988, devendo ser garantida pelo Sistema Único de Saúde (SUS).
Wallace Dos Santos, Yamila Comes, Lucélia Luiz Pereira, Ana Maria Costa, Edgar Merchan-Hamann, Leonor Maria Pacheco Santos   +5 more
doaj   +1 more source

Status of AmeriCorps healthy futures national service programs [PDF]

, 2016
AmeriCorps engages adults in service learning positions within government and non-profit agencies that focus on improving communities. The healthy futures focus area of AmeriCorps’ funding agency, the Corporation for National and Community Service (CNCS),
McNaboe, Jennifer
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