Results 91 to 100 of about 1,627,853 (314)
Girls in IT: How to develop talent and leverage support [PDF]
, 2013 The objectives of this panel are to inform the audience about national and regional initiatives developed by the National Center for Women & Information Technology (NCWIT) to reach out to middle and high school girls; learn from promising experiences in ...
LaBelle, Deborah +5 more
core +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Inland Navigation Technology \u2709 - Digital Technology Impact on Safety and Efficiency [PDF]
, 2009 This workshop discussed the impact of digital technology on inland navigation safety and efficiency from the combined perspective government agencies and waterway operators.
Alexander, Lee
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Nitrogen/argon diluted acetylene and ethylene blue flames under infrared CO2 laser irradiation
AIP Advances, 2011 We investigated changes in emission spectra from nitrogen/argon diluted laminar diffusion acetylene and ethylene blue flames irradiated by a powerful cw infrared CO2 laser.
Peter V. Pikhitsa +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
YAP promotes global mRNA translation to fuel oncogenic growth despite starvation
Experimental and Molecular MedicineYes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) play fundamental roles in stem/progenitor cell expansion during homeostasis, and their dysregulation often leads to tissue overgrowth.
Daehee Hwang +10 more
doaj +1 more source
Gathering Activities of Daily Living Data for Elderly Care in Network Deficient Environments
IEEE AccessElderly care becomes more and more important as elderly populations increase. Many solutions are proposed for monitoring elderly activities of daily living (ADL) or healthcare related data.
Huan-Bang Li +3 more
doaj +1 more source
Implementing the National Bioengineered Food Disclosure Standard [PDF]
, 2018 In July 2016, the National Bioengineered Food Disclosure Law was passed to establish a mandatory national system for disclosing the presence of genetically-engineered material in food (GMOs). The federal law preempts state and local initiatives to create
McAllister, Lesley K.
core +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source