Results 61 to 70 of about 1,947 (140)

Advanced engineering of third-generation lysins and formulation strategies for clinical applications [PDF]

, 2020
One of the possible solutions for the current antibiotic resistance crisis may be found in (often bacteriophage-derived) peptidoglycan hydrolases. The first clinical trials of these natural enzymes, coined here as first-generation lysins, are currently ...
Agren MS, Beller FK, Centers for Disease Prevention and Control, Channabasappa S, Clausen H, Doering TL, Jabbour JF, Jackson JK, O’Neill J., WHO   +9 more
core   +1 more source

Identification of a lipoteichoic acid glycosyltransferase enzyme reveals that GW-domain containing proteins can be retained in the cell wall of Listeria monocytogenes in the absence of lipoteichoic acid or its modifications

, 2016
Listeria monocytogenes is a foodborne Gram-positive bacterial pathogen, and many of its virulence factors are either secreted proteins or proteins covalently or noncovalently attached to the cell wall.
Grundling, A, Karinou, E, Percy, M, Webb, A   +3 more
core   +1 more source

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 21: Suitability of taxonomic units notified to EFSA until September 2024

EFSA Journal, Volume 23, Issue 1, January 2025.
Abstract The qualified presumption of safety (QPS) process was developed to provide a safety assessment approach for microorganisms intended for use in food or feed chains. In the period covered by this Statement, no new information was found that would change the status of previously recommended QPS taxonomic units (TUs).
EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Marianne Chemaly, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Angela Botteon, Baptista Carolina, Barizzone Fulvio, Sandra Correia, Lieve Herman   +28 more
wiley   +1 more source

Emerging role of gut microbiota extracellular vesicle in neurodegenerative disorders and insights on their therapeutic management

iMetaOmics, Volume 1, Issue 2, December 2024.
Gut microbiota extracellular vesicles play (GMEVs) a vital role in maintaining the health of the digestive system and facilitating proper brain functioning. Gut dysbiosis exacerbates gut inflammation, facilitating the entry of harmful substances into the bloodstream.
Adil Hassan, Yin Huang, Mahjabina, Otmilda Hapsari Sudiro, Xiangxiu Wang, Jingqin He, Yan Wei, Xiaoling Liao, Guixue Wang   +8 more
wiley   +1 more source

Genetic Dissection of T4 Lysis [PDF]

, 2014
t is the holin gene for coliphage T4, encoding a 218-amino-acid (aa) protein essential for the inner membrane hole formation that initiates lysis and terminates the phage infection cycle. T is predicted to be an integral membrane protein that adopts an N(
Jessica L. Lawler, Ry Young, Samir H. Moussa   +2 more
core   +2 more sources

Entry of the membrane-containing bacteriophages into their hosts [PDF]

, 2010
Viruses are biological entities able to replicate only within their host cells. Accordingly, entry into the host is a crucial step of the virus life-cycle.
Cvirkaite-Krupovic, Virginija
core  

Evolutionary Genomics of Prokaryotic Viruses [PDF]

, 2010
Evolutionary history of biological entities is recorded within their nucleic acid sequences and can (sometimes) be deciphered by thorough genomic analysis.
Krupovic, Mart
core  

Crystallization Of The CHAP Domain Of The Endolysin From Staphylococcus Aureus Bacteriophage K [PDF]

, 2013
CHAPK is the N-terminal cysteine, histidine-dependent amidohydrolase/peptidase domain (CHAP domain) of the Staphylococcus aureus bacteriophage K endolysin LysK.
Coffey, Aidan, Garcia-Doval, Carmela, Keary, Ruth, Sanz-Gaitero, Marta, van Raaij, Mark J.   +4 more
core   +1 more source

Phage–derived Endolysins as Potential Antibacterials : A Study of Peptidoglycan Hydrolase and Mycolylarabinogalactan Esterase Enzymes [PDF]

, 2019
Bacteriophages, or phages, are viruses that infect bacteria, at the end of their life cycle produce a set of enzymes called endolysins to lyse host cells from within, facilitating the release of the viral progeny.
Abouhmad, Adel
core  

Interaction of the Phage Endolysin PlyC with Model Membranes [PDF]

, 1923
Barros, Marilia, Vennemann, Tarek, Heinrich, Frank, Nelson, Daniel, Lösche, Mathias   +4 more
core   +1 more source