Results 171 to 180 of about 69,844 (264)

GLP‐1 RA Plus SGLT2i Versus Monotherapy in MASLD and Type 2 Diabetes: Three Pairwise Target Trial Emulations

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) have demonstrated cardiovascular and metabolic benefits individually; however, the comparative effectiveness of combination therapy versus monotherapy in patients with metabolic dysfunction‐associated steatotic liver ...
Mohanad A. Alkuwaiti   +11 more
wiley   +1 more source

Efficacy and Safety of Vericiguat in a Real-life Population with Heart Failure after 1 Year of Treatment: The VERITA Study. [PDF]

open access: yesCard Fail Rev
Galván-Ruiz M   +11 more
europepmc   +1 more source

Assessing Associations of Three Types of Higher‐Risk Medication Use and Mortality in Older Adults

open access: yesJournal of the American Geriatrics Society, EarlyView.
Having a medication regimen with polypharmacy was associated with higher risk of mortality among older adults even after accounting for clinical factors and other types of higher‐risk medication use. ABSTRACT Background Higher‐risk medication use—including regimens with polypharmacy, drug–drug interactions (DDIs), and potentially inappropriate ...
Alexander Chaitoff   +3 more
wiley   +1 more source

Prevalence, Comparative Risk, and Predictors of Shock in Children With Multisystem Inflammatory Syndrome Associated With COVID‐19: A Systematic Review and Meta‐Analysis

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Multisystem inflammatory syndrome in children (MIS‐C) is a severe hyperinflammatory condition associated with SARS‐CoV‐2 infection and is frequently complicated by cardiovascular dysfunction, particularly shock. Early recognition of shock in MIS‐C is critical to reduce morbidity and mortality.
Asif Jan   +6 more
wiley   +1 more source

Orthodontic and Maxillofacial Surgery Treatment in Achondroplasia for Orofacial Alterations: A Systematic Review and Preliminary Age‐Stratified Guidelines

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT This systematic review aimed to collect and appraise the clinical outcomes of all orthopaedic, orthodontic and surgical interventions in ACH patients. Following PROSPERO protocol, multiple database sources were searched to December 2024 with no language restrictions for (i) genetically confirmed ACH; (ii) any orthodontic/orthopaedic ...
Marco Farronato   +5 more
wiley   +1 more source

Biobank-Scale Plasma Proteomics Identifies Novel Biomarkers in Hypertrophic Cardiomyopathy. [PDF]

open access: yesCirc Genom Precis Med
Chan JH   +9 more
europepmc   +1 more source

NT‐proBNP as a Predictor of Atrial Fibrillation Recurrence After Cryoballoon, Radiofrequency and Pulsed‐Field Ablation

open access: yesPacing and Clinical Electrophysiology, EarlyView.
Central Illustration: In a study investigating AF recurrence after PVI with RFA, CBA, and PFA, elevated NT‐proBNP emerged as a strong predictor of recurrence within the first year, outperforming other clinical measures. Color‐coded recurrence‐free survival probability charts derived from these data are proposed to support individualized clinical ...
Johannes Bruss   +11 more
wiley   +1 more source

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