Efficacy comparison of dapagliflozin combined with liraglutide versus monotherapy in obese patients with heart failure. [PDF]
Zhou G, Liu A, Hu X, Qi G, Zhang Y.
europepmc +1 more source
Disproportional ventilatory response to incremental exercise in individuals with cerebral palsy
Individuals with cerebral palsy demonstrate a disproportionate ventilatory response during incremental exercise. Compared with typically developing peers, respiratory frequency increases earlier and at comparable exercise intensities, contributing to higher perceived exertion and reduced ventilatory efficiency. At task failure, respiratory frequency is
Linnéa Corell +14 more
wiley +1 more source
Prognostic factors in dogs with presumed degenerative mitral valve disease attending primary care veterinary practices in the UK [PDF]
Club Kennel +5 more
core +2 more sources
Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular‐Kidney‐Metabolic Syndrome
ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Evan Zeitler +4 more
wiley +1 more source
Incremental Prognostic Value of Heart-Type Fatty Acid Binding Protein in Patients With Light Chain Cardiac Amyloidosis: A Prospective Cohort Study. [PDF]
Li X +10 more
europepmc +1 more source
ABSTRACT Aims The fibrosis‐4 (FIB‐4) score is used to identify risk of advanced liver fibrosis. This post hoc analysis investigated its prognostic value for cardiovascular (CV) outcomes and its relevance to the effects of dapagliflozin. Materials and Methods DECLARE‐TIMI 58 was a randomised, placebo‐controlled phase 3 trial investigating dapagliflozin ...
Jan Oscarsson +12 more
wiley +1 more source
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy +7 more
wiley +1 more source
Incremental Value of NT-proBNP Over HCM-AF Score in Risk Stratification for Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy. [PDF]
Gao YP +10 more
europepmc +1 more source
Bioelectrical Impedance in Pediatric Dialysis: Clinical Applications, Limitations, and Opportunities
ABSTRACT Background Optimizing fluid and nutritional management is a cornerstone of care for children with end‐stage kidney disease on dialysis. Inaccurate assessment of hydration status contributes to hypertension, fluid overload, and increased cardiovascular risk, while masking important changes in muscle and fat compartments that affect growth and ...
Marisa Juarez‐Calderon +2 more
wiley +1 more source
Utility of biomarkers in patients with a type 2 myocardial infarction: a systematic review. [PDF]
Gouda P +4 more
europepmc +1 more source

