Results 191 to 200 of about 69,844 (264)

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Longitudinal and cross-sectional associations of myocardial stress markers with kidney function and chronic kidney disease in the BiomarCaRE project. [PDF]

Sci Rep
Lin JS, Zeller T, Koenig W, Jousilahti P, Kee F, Iacoviello L, Tunstall-Pedoe H, Söderberg S, Cesana G, Palmieri L, Salomaa V, de Man Lapidoth J, De Ponti R, Donfrancesco C, Lorenz T, Kuulasmaa K, Blankenberg S, Peters A, Thorand B.   +18 more
europepmc   +1 more source

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, EarlyView.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source

A new approach to an old disease: Ageing, arrhythmogenic substrate and the role of risk‐factor modification in atrial fibrillation

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) prevalence rises sharply with age due to two independent mechanisms. Ageing produces irreversible arrhythmogenic substrate changes through progressive fibrosis, cellular senescence and mitochondrial dysfunction, while modifiable risk factors such as obesity, hypertension, sleep apnoea, diabetes and alcohol use promote ...
Udit Thakur, Jonathan M. Kalman
wiley   +1 more source

Circulating biomarkers improve prediction of postoperative outcome after aortic valve surgery. [PDF]

Front Cardiovasc Med
Demal TJ, Bialczak J, Goßling A, Ojeda FM, Bhadra OD, Sill B, Petersen J, Ludwig S, Grundmann D, Voigtländer L, Waldschmidt L, Hannen L, Schofer N, Blankenberg S, Kirchhof P, Renné T, Conradi L, Reichenspurner H, Girdauskas E, Schaefer A.   +19 more
europepmc   +1 more source

Leptin–cholesterol crosstalk in pregnancy: Mechanistic implications for placental function and cardiometabolic programming

Experimental Physiology, EarlyView.
Abstract Pregnancy requires the coordinated maternal reorganization of lipid and endocrine pathways to sustain fetal growth and anticipate neonatal nutrition. Leptin, produced by adipose tissue and the placenta, acts as an integrative signal linking maternal energy status with trophoblast function and vascular adaptation, while cholesterol provides ...
Julio Flores, Diego Gumera, Andreina Arias, Cristián A. Amador, María José Yañez   +4 more
wiley   +1 more source

Exosomal CNP and CNP-Related microRNAs: An Open Window into Brugada Syndrome? [PDF]

Biomedicines
Cabiati M, Vozzi F, Persiani E, Piacenti M, Rossi A, Sgalippa A, Cecchettini A, Solarino G, Zucchelli G, Mazzocchetti L, Notarstefano P, Guiducci L, Morales MA, Del Ry S.   +13 more
europepmc   +1 more source

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

The Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Comprehensive assessment of novel cardiovascular biomarkers in AF. [PDF]

Europace
Ohlrogge AH, Engler D, Schlieker P, Seum F, Rosebrock K, Nebel N, Csengeri D, Fabritz L, Ziegler A, Blankenberg S, Kirchhof P, Zeller T, Schnabel RB.   +12 more
europepmc   +1 more source

Electrocardiographic Correlates of Myocardial Remodeling After Cardiac Resynchronization Therapy

Pacing and Clinical Electrophysiology, EarlyView.
Christian Toquica, Amulya Gupta, Tucker Morey, Christopher J. Harvey, Seth H. Sheldon, Madhu Reddy, Amit Noheria   +6 more
wiley   +1 more source