Results 11 to 20 of about 164,451 (332)
Pathogenetic justification of sacubitril / valsartan use in respiratory-cardial comorbidity
Patologìâ, 2023 Among the comorbid conditions that significantly worsen quality of life and life expectancy are the chronic obstructive pulmonary disease and heart failure.
T. V. Ashcheulova +3 more
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Biology, 2022 The field of natriuretic peptides (NPs) as an endocrine hormone has been developing since 1979. There are three peptides in humans: atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP), which bind to the guanylyl cyclase-A (GC-A ...
Tomoko Ichiki +2 more
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Mismeasure of C-Type Natriuretic Peptide [PDF]
Clinical Chemistry, 2008 It has been difficult to establish an endocrine role for C-type natriuretic peptide (CNP). Release of CNP from the heart remains to be convincingly demonstrated (1)(2)(3)(4)(5), and data concerning CNP in cardiac disease have been conflicting, possibly because of specificity problems in measurement of CNP.
Nielsen, S.J. +2 more
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Molecular Mechanism of Blood Pressure Regulation through the Atrial Natriuretic Peptide
Biology, 2022 Natriuretic peptides, including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), have cardioprotective effects and regulate blood pressure in mammals.
Takeshi Tokudome, Kentaro Otani
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AC-NP: a novel chimeric peptide with natriuretic and vasorelaxing actions. [PDF]
PLoS ONE, 2011 The aim of this study was to evaluate the cardiovascular and renal activities of a newly designed natriuretic peptide (NP). Here, we engineered a novel 28-amino acid chimeric peptide, termed AC-NP that combined the 17-amino acid ring of C type ...
Bao-Ying Chen +9 more
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Do N-Terminal Pro-C-Type Natriuretic Peptide Levels Relate to Severity of Preeclampsia?
International Journal of Hypertension, 2020 Aim. To compare the plasma N-terminal pro-C-type natriuretic peptide concentrations of normotensive pregnant women, patients with mild preeclampsia, and patients with severe preeclampsia. Methods.
Dogan Vatansever +4 more
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Frontiers in Veterinary Science, 2022 During infection, the infected tissue secretes a variety of endogenous peptides to resist further invasion of pathogens. Among these endogenous peptides, the natriuretic peptides and the antimicrobial peptides attracted the most attention.
Mingzhen Fan +15 more
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C-Type Natriuretic Peptides in Coronary Disease [PDF]
Clinical Chemistry, 2017 Abstract AIMS C-type natriuretic peptide (CNP) is a paracrine growth factor expressed in the vascular endothelium. Although upregulated in atheromatous arteries, the predictive value of plasma CNP products for outcome in coronary disease is unknown.
Richard W. Troughton +8 more
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Roles of Natriuretic Peptides and the Significance of Neprilysin in Cardiovascular Diseases
Biology, 2022 Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) activate the guanylyl cyclase A receptor (GC-A), which synthesizes the second messenger cGMP in a wide variety of tissues and cells.
Hitoshi Nakagawa, Yoshihiko Saito
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Frontiers in Molecular Neuroscience, 2022 C-type natriuretic peptide (CNP) is highly expressed in the central nervous system (CNS) and key to neuronal development; however, a broader role for CNP in the CNS remains unclear.
Cristina Perez-Ternero +7 more
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