Signaling pathways involved in renal oxidative injury: role of the vasoactive peptides and the renal dopaminergic system [PDF]
The physiological hydroelectrolytic balance and the redox steady state in the kidney are accomplished by an intricate interaction between signals from extrarenal and intrarenal sources and between antinatriuretic and natriuretic factors.
Choi, Marcelo Roberto+6 more
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Natriuretic peptides and integrated risk assessment for cardiovascular disease. an individual-participant-data meta-analysis [PDF]
BACKGROUND: Guidelines for primary prevention of cardiovascular diseases focus on prediction of coronary heart disease and stroke. We assessed whether or not measurement of N-terminal-pro-B-type natriuretic peptide (NT-proBNP) concentration could enable ...
Adam S, Butterworth+53 more
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Role of C-type natriuretic peptide in the function of normal human sperm
C-type natriuretic peptide (CNP) is a newly discovered type of local regulatory factor that mediates its biological effects through the specific, membrane-bound natriuretic peptide receptor-B (NPR-B).
Hui Xia+5 more
doaj +1 more source
C-type natriuretic peptide: A new cardiac mediator [PDF]
Natriuretic peptides are endogenous hormones released by the heart in response to myocardial stretch and overload. While atrial and brain natriuretic peptides (ANP, BNP) were immediately considered cardiac hormones and their role was well-characterized and defined in predicting risk in cardiovascular disease, evidence indicating the role of C-type ...
openaire +3 more sources
Measurement of Pro-C-Type Natriuretic Peptide in Plasma [PDF]
Accurate measurement of peptides derived from pro-C-type natriuretic peptide (proCNP) in human plasma has been difficult for several reasons. Low plasma concentrations necessitate high assay sensitivity. In addition, sufficient specificity can be difficult because of the close sequence homology of CNP with atrial natriuretic peptide (ANP) and B-type ...
Jens F. Rehfeld+5 more
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Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model [PDF]
© 2013 Peake et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Achan, P+8 more
core +2 more sources
Predictive Value of Depressive Symptoms for All-Cause Mortality: Findings From the PRIME Belfast Study Examining the Role of Inflammation and Cardiovascular Risk Markers. [PDF]
OBJECTIVES: To improve understanding about the potential underlying biological mechanisms in the link between depression and all-cause mortality and to investigate the role that inflammatory and other cardiovascular risk factors may play in the ...
Appleton, Katherine+9 more
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Natriuretic peptide receptor-C is up-regulated in the intima of advanced carotid artery atherosclerosis [PDF]
OBJECTIVE: Natriuretic peptide receptor-C (NPR-C/NPR-3) is a cell surface protein involved in vascular remodelling that is up-regulated in atherosclerosis. NPR-C expression has not been well characterized in human carotid artery occlusive lesions.
Abendschein, Dana R+7 more
core +3 more sources
NPs/NPRs Signaling Pathways May Be Involved in Depression-Induced Loss of Gastric ICC by Decreasing the Production of mSCF. [PDF]
It is well known that natriuretic peptides (NPs) are involved in the regulation of gastrointestinal motility. Interstitial cells of Cajal (ICC) are the pacemaker cells of gastrointestinal motility and gastrointestinal dyskinesia is one of the important ...
Xue-Lian Lin+6 more
doaj +1 more source
Despite the extensive prevalence of hypertension and its established role as a leading risk factor for various heart diseases, there remains a significant gap in understanding the intricate mechanisms and physiological markers involved in the condition.
Amna Adil Mohammed, Maryam I. Salman
doaj +1 more source