Results 11 to 20 of about 123,362 (289)

Pathogenetic justification of sacubitril / valsartan use in respiratory-cardial comorbidity

Patologìâ, 2023
Among the comorbid conditions that significantly worsen quality of life and life expectancy are the chronic obstructive pulmonary disease and heart failure.
T. V. Ashcheulova, K. M. Kompaniiets, N. M. Herasymchuk, I. V. Sytina   +3 more
doaj   +1 more source

Natriuretic Peptides

Journal of the American College of Cardiology, 2007
Natriuretic peptides (NPs) are released from the heart in response to pressure and volume overload. B-type natriuretic peptide (BNP) and N-terminal-proBNP have become important diagnostic tools for assessing patients who present acutely with dyspnea. The NP level reflects a compilation of systolic and diastolic function as well as right ventricular and
Daniels, Lori B., Maisel, Alan S.
openaire   +4 more sources

zDHHC9 Regulates Cardiomyocyte Rab3a Activity and Atrial Natriuretic Peptide Secretion Through Palmitoylation of Rab3gap1

JACC: Basic to Translational Science, 2023
Summary: Production and release of natriuretic peptides by the stressed heart reduce cardiac workload by promoting vasodilation, natriuresis, and diuresis, which has been leveraged in the recent development of novel heart-failure pharmacotherapies, yet ...
Kobina Essandoh, PhD, Arasakumar Subramani, MS, Olivia A. Ferro, MS, James P. Teuber, BS, Sribharat Koripella, Matthew J. Brody, PhD   +5 more
doaj   +1 more source

Natriuretic peptides: Diagnostic and therapeutic use

Indian Journal of Endocrinology and Metabolism, 2011
Natriuretic peptides (NPs) are hormones which are mainly secreted from heart and have important natriuretic and kaliuretic properties. There are four different groups NPs identified till date [atrial natriuretic peptide (ANP), B-type natriuretic peptide (
Kaushik Pandit, Pradip Mukhopadhyay, Sujoy Ghosh, Subhankar Chowdhury   +3 more
doaj   +1 more source

Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor

eLife, 2023
Natriuretic peptide signaling has been implicated in a broad range of physiological processes, regulating blood volume and pressure, ventricular hypertrophy, fat metabolism, and long bone growth.
Arun Devotta, Hugo Juraver-Geslin, Casey Griffin, Jean-Pierre Saint-Jeannet   +3 more
doaj   +1 more source

Potential applications of natriuretic peptide system in cardiovascular regenerative medicine [PDF]

CellR4, 2022
Cardiovascular diseases are among the major causes of death worldwide. These diseases can be described as circumstances in which cell loss and injury exceed the capacity for regeneration and repair.
M. Öztop
doaj   +1 more source

Blockade of the natriuretic peptide clearance receptor attenuates proteinuria in a mouse model of focal segmental glomerulosclerosis

Physiological Reports, 2021
Glomerular podocytes play a key role in proteinuric diseases. Accumulating evidence suggests that cGMP signaling has podocyte protective effects. The major source of cGMP generation in podocytes is natriuretic peptides.
Liming Wang, Yuping Tang, Anne F. Buckley, Robert F. Spurney   +3 more
doaj   +1 more source

N- terminal pro brain natriuratic peptide (nt-probnp) in apparently healthy subjects compared to metabolic syndrome subjects

Advanced Medical Journal, 2022
Background and objectives: B –type natriuretic peptide is synthesized in myocardial cells to respond to increased wall stress in association with heart failure or acute myocardial ischemia.
Zaidan Azeez Hasan, Dhia Mustafa Sulaiman   +1 more
doaj   +1 more source

B-type natriuretic peptide predicts long-term prognosis in a cohort of critically Ill patients

Heart International, 2011
B-type natriuretic peptide is an important prognostic marker in heart failure. However, there are limited data for its value in non-cardiac intensive care unit patients, namely regarding long-term prognosis. We investigated the long-term prognostic value
Jorge Pimentel, Eduardo Sousa, Elisabete Jorge, Rui Baptista   +3 more
doaj   +1 more source

Natriuretic Peptide-Based Novel Therapeutics: Long Journeys of Drug Developments Optimized for Disease States

Biology, 2022
The field of natriuretic peptides (NPs) as an endocrine hormone has been developing since 1979. There are three peptides in humans: atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP), which bind to the guanylyl cyclase-A (GC-A ...
Tomoko Ichiki, Atsushi Jinno, Yoshihisa Tsuji   +2 more
doaj   +1 more source