Results 11 to 20 of about 1,072,475 (388)

Female-Specific Association of Plasma N-Terminal Pro-Brain Natriuretic Peptide With Organ Dysfunction and Prognosis in Sepsis: A Retrospective Study

Critical Care Explorations, 2021
Objectives:. The plasma level of N-terminal pro-brain natriuretic peptide is regulated by sex hormones. It has been controversial whether N-terminal pro-brain natriuretic peptide is a prognosis marker for sepsis.
Shuangyi Yin, PhD, Yijie Zhang, MD, Yu Guo, MD, Qing Bai, MD, Zhibo Lu, MD, Na Chen, MD, Edmund J. Miller, PhD, Wei Li, MD, PhD   +7 more
doaj   +1 more source

Molecular Mechanism of Blood Pressure Regulation through the Atrial Natriuretic Peptide

Biology, 2022
Natriuretic peptides, including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), have cardioprotective effects and regulate blood pressure in mammals.
Takeshi Tokudome, Kentaro Otani
doaj   +1 more source

Transcription of brain natriuretic peptide and atrial natriuretic peptide genes in human tissues [PDF]

, 1994
We have compared the expression of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) genes in various human tissues using a quantitative polymerase chain reaction technique.
Dagnino, L., Gerbes, Alexander L., Nemer, M., Nguyen, T.   +3 more
core   +5 more sources

Pathogenetic justification of sacubitril / valsartan use in respiratory-cardial comorbidity

Patologìâ, 2023
Among the comorbid conditions that significantly worsen quality of life and life expectancy are the chronic obstructive pulmonary disease and heart failure.
T. V. Ashcheulova, K. M. Kompaniiets, N. M. Herasymchuk, I. V. Sytina   +3 more
doaj   +1 more source

Factors associated with plasma antigen carbohydrate 125 and amino-terminal pro-B-type natriuretic peptide concentrations in acute heart failure

European heart journal. Acute cardiovascular care, 2020
Background: Plasma amino-terminal pro-B-type natriuretic peptide and antigen carbohydrate 125 levels are positively associated with a higher risk of adverse clinical outcomes in acute heart failure.
G. Miñana, R. de la Espriella, A. Mollar, E. Santas, E. Núñez, E. Valero, V. Bodí, F. Chorro, A. Fernández-Cisnal, Jorge Martí-Cervera, J. Sanchis, A. Bayés‐Genís, J. Núñez   +12 more
semanticscholar   +1 more source

Roles of Natriuretic Peptides and the Significance of Neprilysin in Cardiovascular Diseases

Biology, 2022
Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) activate the guanylyl cyclase A receptor (GC-A), which synthesizes the second messenger cGMP in a wide variety of tissues and cells.
Hitoshi Nakagawa, Yoshihiko Saito
doaj   +1 more source

A novel natriuretic peptide [PDF]

BMC Pharmacology, 2011
Background Receptors for the natriuretic peptides (NPs) ANP, BNP and CNP are highly expressed in lung, suggesting that this organ is an important physiological target for NP signalling. By stimulating vasoand bronchodilation and inhibiting cell proliferation and fibrotic processes, NPs may have therapeutic potential in various lung diseases. Mechanisms
Ralf Middendorff, Fritz Buck, Dieter Müller, Hanna Höfeld   +3 more
openaire   +2 more sources

Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor

eLife, 2023
Natriuretic peptide signaling has been implicated in a broad range of physiological processes, regulating blood volume and pressure, ventricular hypertrophy, fat metabolism, and long bone growth.
Arun Devotta, Hugo Juraver-Geslin, Casey Griffin, Jean-Pierre Saint-Jeannet   +3 more
doaj   +1 more source

Natriuretic Peptide-Based Novel Therapeutics: Long Journeys of Drug Developments Optimized for Disease States

Biology, 2022
The field of natriuretic peptides (NPs) as an endocrine hormone has been developing since 1979. There are three peptides in humans: atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP), which bind to the guanylyl cyclase-A (GC-A ...
Tomoko Ichiki, Atsushi Jinno, Yoshihisa Tsuji   +2 more
doaj   +1 more source

Heart Failure Association of the European Society of Cardiology practical guidance on the use of natriuretic peptide concentrations

European Journal of Heart Failure, 2019
Natriuretic peptide [NP; B‐type NP (BNP), N‐terminal proBNP (NT‐proBNP), and midregional proANP (MR‐proANP)] concentrations are quantitative plasma biomarkers for the presence and severity of haemodynamic cardiac stress and heart failure (HF).
C. Mueller, K. McDonald, R. de Boer, A. Maisel, J. Cleland, N. Kozhuharov, A. Coats, M. Metra, A. Mebazaa, F. Ruschitzka, M. Lainščak, G. Filippatos, P. Seferovic, W. Meijers, A. Bayés‐Genís, T. Mueller, M. Richards, J. Januzzi   +17 more
semanticscholar   +1 more source