Natriuretic peptides: Diagnostic and therapeutic use
Indian Journal of Endocrinology and Metabolism, 2011 Natriuretic peptides (NPs) are hormones which are mainly secreted from heart and have important natriuretic and kaliuretic properties. There are four different groups NPs identified till date [atrial natriuretic peptide (ANP), B-type natriuretic peptide (
Kaushik Pandit +3 more
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Physiological Reports, 2021 Glomerular podocytes play a key role in proteinuric diseases. Accumulating evidence suggests that cGMP signaling has podocyte protective effects. The major source of cGMP generation in podocytes is natriuretic peptides.
Liming Wang +3 more
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Potential applications of natriuretic peptide system in cardiovascular regenerative medicine [PDF]
CellR4, 2022 Cardiovascular diseases are among the major causes of death worldwide. These diseases can be described as circumstances in which cell loss and injury exceed the capacity for regeneration and repair.
M. Öztop
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Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]
, 2014 BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P +5 more
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Journal of the American College of Cardiology, 2007 Natriuretic peptides (NPs) are released from the heart in response to pressure and volume overload. B-type natriuretic peptide (BNP) and N-terminal-proBNP have become important diagnostic tools for assessing patients who present acutely with dyspnea. The NP level reflects a compilation of systolic and diastolic function as well as right ventricular and
Alan S. Maisel, Lori B. Daniels
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C-Type Natriuretic Peptide: A Multifaceted Paracrine Regulator in the Heart and Vasculature
International Journal of Molecular Sciences, 2019 C-type natriuretic peptide (CNP) is an autocrine and paracrine mediator released by endothelial cells, cardiomyocytes and fibroblasts that regulates vital physiological functions in the cardiovascular system.
A. Moyes, A. Hobbs
semanticscholar +1 more source
Natriuretic peptides and cardiovascular damage in the metabolic syndrome. Molecular mechanisms and clinical implications [PDF]
, 2010 Natriuretic peptides are endogenous antagonists of vasoconstrictor and salt- and water-retaining systems in the body's defence against blood pressure elevation and plasma volume expansion, through direct vasodilator, diuretic and natriuretic properties ...
ALONZO, ALESSANDRO +4 more
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Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure.
New England Journal of Medicine, 2002 BACKGROUND B-type natriuretic peptide is released from the cardiac ventricles in response to increased wall tension. METHODS We conducted a prospective study of 1586 patients who came to the emergency department with acute dyspnea and whose B-type ...
A. Maisel +17 more
semanticscholar +1 more source
AC-NP: a novel chimeric peptide with natriuretic and vasorelaxing actions. [PDF]
PLoS ONE, 2011 The aim of this study was to evaluate the cardiovascular and renal activities of a newly designed natriuretic peptide (NP). Here, we engineered a novel 28-amino acid chimeric peptide, termed AC-NP that combined the 17-amino acid ring of C type ...
Bao-Ying Chen +9 more
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Molecular Implications of natriuretic peptides in the protection from hypertension and target organ damage development [PDF]
, 2019 The pathogenesis of hypertension, as a multifactorial trait, is complex. High blood pressure levels, in turn, concur with the development of cardiovascular damage.
Forte, Maurizio +3 more
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