Results 61 to 70 of about 8,285,443 (358)

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Hume y la naturalización de la religión

open access: yesTópicos, 2013
David Hume wrote several works on religious matters. His Dialogues concerning natural religion present his ideas on natural theology and the so-called natural religion. My aim in this study is to underline some aspects of his Natural History of Religion,
Juan Andrés Mercado
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The Multifaceted Aspects of Ecosystem Integrity

open access: yesEcology and Society, 1997
The need to reduce human impacts on ecosystems creates pressure for adequate response, but the rush to solutions fosters the oversimplification of such notions as sustainable development and ecosystem health.
Giulio A. De Leo, Simon A. Levin
doaj   +1 more source

The nature of natural units [PDF]

open access: yesNature Physics, 2016
Nick van Remortel demystifies natural unit systems — and advises what to do when you see a mass expressed in GeV.
openaire   +3 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Innovations in Groundwater Remediation

open access: yesEDIS, 2003
Innovative research conducted by a University of Florida (UF) faculty team offers an efficient and less costly approach to remediating contaminated groundwater.
Center for Natural Resources
doaj   +2 more sources

Naturalness as a reasonable scientific principle in fundamental physics [PDF]

open access: yesarXiv, 2019
I aim to clarify the physical content and significance of naturalness. Physicists' earliest understanding of naturalness, as an autonomy of scales (AoS) requirement provides the most cogent definition of naturalness and I will assert that i) this provides a uniform notion which undergirds a myriad prominent naturalness conditions, ii) this is a ...
arxiv  

The Influence of Colorants, Flavorants and Product Identity on Perceptions of Naturalness

open access: yesFoods, 2019
Natural foods are important to consumers, yet frustrating to producers due to the lack of a formal definition of “natural”. Previous work has studied how consumers define naturalness and how they rate the naturalness of various products, but ...
Tyler Murley, Edgar Chambers
doaj   +1 more source

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