Results 171 to 180 of about 312,278 (301)

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Editorial: Natural Plant Antioxidants and Cardiovascular Disease

Frontiers in Physiology, 2022
Claudia Castro
doaj   +1 more source

The Combination of Mineral Salts and Natural Antioxidants Agents Is Highly Effective in Atopic Dermatitis. [PDF]

Clin Cosmet Investig Dermatol
Yori F, Sarmiento C, Gimeno Beltran J, Umbert I.   +3 more
europepmc   +1 more source

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu, Yang Liu, Kang Kang, Jianfeng Yu, Xiaowei Xia, Yaoge Deng, Yingjie Lu, Huilin Yang, Lisong Li, Wu Xu, Yijian Zhang, Xuesong Zhu   +11 more
wiley   +1 more source

Green-synthesized natural antioxidants in poultry and livestock feed: enhancing oxidative stability and animal welfare. [PDF]

Front Vet Sci
Nefzi K, BenSouf I, Saidani M, Darej C, Bejaoui B, Ben Larbi M, M'Hamdi N, Lequart V, Joly N, Martin P.   +9 more
europepmc   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Antioxidants: Natural Antibiotics

, 2019
Raza, Naqvi, Syed Ali, Sana, Nadeem,, Sana, Komal,, Ali, Asad Naqvi, Syed, Samee, Mubarik, Muhammad, Sajid, Yaqub Qureshi,, Shahzad, Ahmad,, Ali, Abbas,, Naeem-Ul-Haq, Khan,, Shujat, Raza, Syed, Nosheen, Aslam,   +10 more
openaire   +4 more sources

Macro-micromorphological, anatomical, and phytochemical characterization of Cucumis melo var. agrestis Naudin: a potential source of natural antioxidants. [PDF]

Sci Rep
Shehata FA, Hamdy R, Garf IE, Megahed EM.   +3 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Evaluation of antifungal and antimycotoxigenic activity of selected natural antioxidants against Fusarium culmorum: in vitro and in planta assays. [PDF]

J Sci Food Agric
Oufensou S, Fabbri D, Dettori MA, Carta P, Azara E, Ugone V, Balmas V, Malbrán I, Migheli Q.   +8 more
europepmc   +1 more source