Results 201 to 210 of about 145,382 (255)

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Interfacial Growth of 420 nm Ultrathin and Dense MOFs for Composite Electrolyte to Reduce Li+ Conduction Resistance and Inhibit Lithium Dendrite

Advanced Science, EarlyView.
In this work, an interfacial growth method using PVDF‐HFP enables controlled permeation of 2‐methylimidazole to react with Co2+, forming an ultrathin (420 nm) ZIF‐67 layer by precisely tuning the reaction time. This dense layer promotes lithium salt dissociation and suppresses dendrite growth, while its ultrathin nature reduces Li+ transport resistance,
Xinhong Qi, Zhaokai Rui, Shichen Zhang, Yihang Li, Ziyi Xin, Mengjuan Li, Lu Gao, Yuchen He, Xiaobin Jiang, Xiangcun Li, Gaohong He   +10 more
wiley   +1 more source

The Interplay of Protein Aggregation, Genetics, and Oxidative Stress in Alzheimer's Disease: Role for Natural Antioxidants and Immunotherapeutics. [PDF]

Antioxidants (Basel)
Ali J, Choe K, Park JS, Park HY, Kang H, Park TJ, Kim MO.   +6 more
europepmc   +1 more source

Incorporation of Cactus Berry (<i>Myrtillocactus geometrizans</i>) and Red Prickly Pear (<i>Opuntia ficus-indica</i> L. Mill.) Mixtures on Sausages Elaborated from White-Striped Broiler Breast as Possible Natural Antioxidants. [PDF]

Foods
López-Hernández LH, Navarro-Olivera AA, Calderón-Oliver M, Villalobos-Delgado LH.   +3 more
europepmc   +1 more source

Potentials of Natural Antioxidants in Reducing Inflammation and Oxidative Stress in Chronic Kidney Disease. [PDF]

Antioxidants (Basel)
Lee OYA, Wong ANN, Ho CY, Tse KW, Chan AZ, Leung GP, Kwan YW, Yeung MHY.   +7 more
europepmc   +1 more source

Natural Antioxidants Reduce Oxidative Stress and the Toxic Effects of RNA-CUG_(exp) in an Inducible Glial Myotonic Dystrophy Type 1 Cell Model. [PDF]

Antioxidants (Basel)
Morales F, Vargas D, Palma-Jiménez M, Rodríguez EJ, Azofeifa G, Hernández-Hernández O.   +5 more
europepmc   +1 more source

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Fungi-derived natural antioxidants

Critical Reviews in Food Science and Nutrition, 2023
In humans, exogenous antioxidants aid the endogenous antioxidant system to detoxify excess ROS generated during oxidative stress, thereby protecting the body against various diseases and stressful conditions. The majority of natural antioxidants available on the consumer market are plant-based; however, fungi are being recognized as alternative sources
Nazli Pinar Arslan, Pranav Dawar, Seyda Albayrak, Meryem Doymus, Fakhrul Azad, Nevzat Esim, Mesut Taskin   +6 more
openaire   +3 more sources