Results 51 to 60 of about 18,013 (253)
Bioactivity and toxicity of coumarins from African medicinal plants
Frontiers in PharmacologyIntroduction: Coumarins are naturally occuring metabolites from plants and a few micro-organisms. They have been widely used in the food and drug industry in their natural or synthetic forms.
Godwin Anywar, Emmanuel Muhumuza
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Advanced Science, EarlyView.In this review, the classification and development history of the volatile solid and solvent additives are comprehensively summarized, the underlying mechanisms of morphology optimization are discussed, and a summary of volatile additive‐induced improvements in interfacial layer performance is provided.
Jianqiang Qin +7 more
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Molecules, 2015 Coumarin is a natural compound well known for its phytotoxic potential. In the search for new herbicidal compounds to manage weeds, three synthetic derivatives bearing the coumarin scaffold (1–3), synthesized by a carbonylative organometallic approach ...
Fabrizio Araniti +6 more
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Advanced Science, EarlyView.In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang +20 more
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Evaluation of Halogenated Coumarins for Antimosquito Properties
The Scientific World Journal, 2014 Mosquitoes are the major vectors of parasites and pathogens affecting humans and domestic animals. The widespread development of insecticide resistance and negative environmental effects of most synthetic compounds support an interest in finding and ...
Venugopala K. Narayanaswamy +5 more
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Molecules, 2019 In order to enrich and separate three coumarins (columbianetin acetate, osthole and columbianadin) from Angelicae Pubescentis Radix (APR), an efficient method was established by combining macroporous resins (MARs) with preparative high-performance liquid
Yuqiao Yang +6 more
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Coumarin carbonic anhydrase inhibitors from natural sources
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Coumarins constitute a relatively new class of inhibitors of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), possessing a unique inhibition mechanism, acting as “prodrug inhibitors.” They undergo the hydrolysis of the lactone ring mediated by the ...
Claudiu T. Supuran
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Advanced Intelligent Discovery, EarlyView.Sequential multicolor fluorescence imaging in dynamic microsystems is constrained by acquisition speed and excitation dose. This study introduces a real‐time framework to reconstruct spectrally separated channels from reduced cross‐channel acquisitions (frames containing mixed spectral contributions).
Juan J. Huaroto +3 more
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Natural immune boosters: coumarins as emerging potentiators of immunity in drug discovery
Phytomedicine PlusBackground: In the wake of increasing global health threats, bolstering host immunity has become a central focus in drug discovery. Coumarins, a class of phenolic compounds abundantly found in plants, have emerged as promising candidates due to their ...
Yasser Fakri Mustafa
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PharmaceuticsCoumarins are natural organic compounds widely found in plants that show promising anticancer properties. This article reviews the current research on the mechanisms of action of coumarins in cancer therapy, including the induction of apoptosis ...
Tomasz Piotr Kubrak +2 more
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