Results 61 to 70 of about 1,272,070 (265)

Morphodynamics of supercritical high-density turbidity currents

open access: yes, 2012
Seafloor and outcrop observations combined with numerical and physical experiments show that turbidity currents are likely 1) to be in a supercritical flow state and 2) to carry high sediment concentrations (being of high-density). The thesis starts with
Sedimentology   +3 more
core  

Recent origin of low trabecular bone density in modern humans [PDF]

open access: yes, 2014
Humans are unique, compared with our closest living relatives (chimpanzees) and early fossil hominins, in having an enlarged body size and lower limb joint surfaces in combination with a relatively gracile skeleton (i.e., lower bone mass for our body ...
Chirchira, Habiba   +13 more
core   +1 more source

A demo-genetic model shows how silviculture reduces natural density-dependent selection in tree populations. [PDF]

open access: yesEvol Appl, 2023
Godineau C   +8 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

A numerical analysis of buoyancy-driven melting and freezing

open access: yes, 2004
A numerical investigation of transient natural convective heat transfer with coupled phase change is presented. The numerical model attempts to capture the solid-fluid interface using a fixed-grid solution and is applied to two pure substance cases found
Scanlon, T.J., Stickland, M.T.
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

¿Era la industria eléctrica de entreguerras un monopolio natural? Evidencia a partir de la Sociedad Hidroeléctrica Española [PDF]

open access: yes, 2005
En los últimos años se ha cuestionado la condición de monopolio natural de la industria eléctrica. La fase de generación ya no es considerada como un monopolio natural, y se debate que la fase de distribución lo sea. Este trabajo parte de las principales
Anna Maria Aubanell Jubany   +1 more
core   +1 more source

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