Results 101 to 110 of about 1,274,911 (307)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
A alimentação da população e a manutenção do potencial produtivo dos recursos naturais [PDF]
, 2008 This work analysis the most important determinants of supply and demand for food. On the supply side, special attention is given to the quantity and quality of resources available on earth, the technological progress, the governmental priorities and ...
Pinheiro, António C. +1 more
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Arthritis Care &Research, EarlyView.Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in electronic health records. Methods We searched Medline, Embase, and Cochrane Central Register for Controlled Trials databases and included studies that validated case definitions against a ...
Constanza Saka‐Herrán +10 more
wiley +1 more source
Infaunal bivalves exhibit resilience to ocean acidification but remain sensitive to food supply
Frontiers in Marine ScienceSoft-sediment habitats are crucial for marine coastal ecosystems, supporting diverse biodiversity both above and below the sediment. Ocean acidification, driven by rising CO2 and nutrient influx, enhances heterotrophic metabolism, raising CO2 levels and ...
Montserrat Antivero +7 more
doaj +1 more source
High global food prices The challenges and opportunities: IFPRI 2007-2008 Annual Report Essay [PDF]
"High food prices are not only causing a humanitarian crisis, but also putting at risk the development potential of millions of people. Global agriculture markets are undergoing structural changes, and the next three to four years will pose great ...
Sheeran, Josette
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Arthritis Care &Research, EarlyView.Objective We evaluated the ability of the Renal Activity Index for Lupus (RAIL) to discriminate active lupus nephritis (LN) in adult patients with active systemic lupus erythematosus (SLE) and differentiate LN treatment response. Methods Urine samples from adults with biopsy‐proven active class III and IV LN from TULIP‐LN (active LN group ...
Hermine I. Brunner +12 more
wiley +1 more source
Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus
Arthritis Care &Research, EarlyView.Objective Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...
Jay Patel +8 more
wiley +1 more source
Milk Supply Chain and Efficiency of Smallholder Dairy Producers in Pakistan [PDF]
Many developing countries are re-orienting their production and marketing systems by linking local agri-producers with organized supply chain networks and supermarkets to meet increasing consumer demands. However, the existing literature is silent on the
Abid A. Burki, Mushtaq A. Khan
core +1 more source
Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials
Advanced Engineering Materials, EarlyView.Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai +2 more
wiley +1 more source
Sustainable agricultural development strategies in fragile lands: [PDF]
Current trends in demography, agricultural production and rural environment in the developing countries suggest that so-called "marginal lands" must play a larger and probably growing role in food supply and economic development for the foreseeable ...
Hazell, P. B. R., Scherr, Sara J.
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