Results 41 to 50 of about 1,274,911 (307)

Disentangling ecosystem services perception by stakeholders: An integrative assessment based on land cover

Ecological Indicators, 2021
Understanding where ecosystem services (ES) are and quantifying their supply using stakeholderś information is key for effective sustainable management.
Pedro Cabral, Felipe S. Campos, João David, Ursula Caser   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

An experience in growing crossbreed age-1 carp (Cyprinus carpio Linnaeus, 1758) using non-traditional technology

Ribogospodarsʹka Nauka Ukraïni
Purpose. To characterize the conditions for growing crossbreed age-1 carp in polyculture using non-traditional technology and to carry out a comparative analysis of productive parameters in comparison with a pure line. Methodology.
М. Ostapchuk, А. Тuchapska, R. Konopelskyi, H. Kurinenko, I. Hrytsyniak   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Finding Ways to Improve Australia’s Food Security Situation

Agriculture, 2015
Although Australia exports more than half of its agricultural production, there are food security problems as the current food supply systems in Australia fail to deliver healthy diets to all Australians and fail to protect the natural resources on which
Quentin Farmar-Bowers
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

How does price insurance alleviate the fluctuation of agricultural product market? A dynamic analysis based on cobweb model

Agricultural Economics (AGRICECON), 2023
Food security is of great importance to all countries. Correspondingly, agricultural price insurance is an important tool to maintain food security. This study adopts the traditional spider web model to establish a mathematical framework for exploring ...
Jianru Fu, Ruiyuan Shen, Chao Huang
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Assessment of Ecosystem Services Supply and Demand (Mis)matches for Urban Ecological Management: A Case Study in the Zhengzhou–Kaifeng–Luoyang Cities

Remote Sensing, 2022
Accurate supply and demand matching of ecosystem services (ESs) is important for managing regional ecosystems. On the basis of remote-sensing, meteorological, and socio-economic data, we mapped the supply, demand, and matching status of four ESs (i.e ...
Dong Xue, Zhaojun Wang, Yuan Li, Mengxue Liu, Hejie Wei   +4 more
doaj   +1 more source