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What is natural in natural killer cells?
Immunology Letters, 2006Denomination is a not a trivial issue in human activities in general, and in science in particular. Natural killer (NK) cells have been originally characterized as cytolytic effector lymphocytes present in mouse spleen and human peripheral blood. The "NK" name was originally coined after the NK cell's ability to kill targets cells without requirement ...
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Natural Killer Cells for Osteosarcoma
2014Natural killer (NK) cells are lymphocytes of the innate immune system that have the ability to recognize malignant cells through detection of a variety of cell-surface indicators of stress and danger. Once activated through such recognition, NK cells release cytokines and induce target cell lysis through a variety of mechanisms.
Nidale Tarek, Dean A. Lee
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2016
In recent years, roles of the immune system in immune surveillance of cancer have been explored. And natural killer (NK) cells are considered to be critical players in anticancer immunity. However, cancers are able to develop mechanisms to escape NK cell attack or to induce defective NK cells.
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In recent years, roles of the immune system in immune surveillance of cancer have been explored. And natural killer (NK) cells are considered to be critical players in anticancer immunity. However, cancers are able to develop mechanisms to escape NK cell attack or to induce defective NK cells.
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Natural Killer T Cells and Asthma
New England Journal of Medicine, 2006Invariant natural killer T cells, originally characterized in mice and more recently defined in humans, are a unique, conserved T-cell sublineage possessing a rearrangement of the T-cell antigen receptor (Vα14Jα18 in mice and Vα24Jα18 in humans). Human natural killer T cells also have an invariant β chain (Vβ11). Vα24Vβ11 binds to glycolipids presented
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Natural killer cells and pregnancy
Nature Reviews Immunology, 2002The fetus is considered to be an allograft that, paradoxically, survives pregnancy despite the laws of classical transplantation immunology. There is no direct contact of the mother with the embryo, only with the extraembryonic placenta as it implants in the uterus.
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2009
This chapter on natural killer cells is an introduction to signalling in cells that exert control over an amazing number of systems. Getting started requires concentration.
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This chapter on natural killer cells is an introduction to signalling in cells that exert control over an amazing number of systems. Getting started requires concentration.
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Harnessing natural killer cells for cancer immunotherapy: dispatching the first responders
Nature Reviews Drug Discovery, 2022Nicholas A Maskalenko +2 more
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Killer whale ecotypes: is there a global model?
Biological Reviews, 2013P J Nico De Bruyn +2 more
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Multifunctional Natural Killer Cell Engagers Targeting NKp46 Trigger Protective Tumor Immunity
Cell, 2019Laurent Gauthier +2 more
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