Results 131 to 140 of about 224,959 (265)

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Genetic Variation Underlying CSF Natural Killer T-Cell Frequency in Inflammatory CNS Diseases: A Genome-Wide Association Study. [PDF]

Neurol Neuroimmunol Neuroinflamm
Wirsching L, Pukaj A, Held F, Makarov C, Kalluri SR, Grummel V, Peters L, Knier B, Korn T, Afzali AM, Hemmer B, Gasperi C.   +11 more
europepmc   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

Advanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang, Zihao An, Honglu Cai, Congsun Li, Jiaxuan Zou, Wushi Cui, Wentao Chen, Tao Zhang, Shicheng Wang, Zizhan Su, Jian Xiao, Tao Sun, Bin Hu, Min Cheng, Zhongru Gou, Jianbin Xu, An Liu, Haobo Wu   +17 more
wiley   +1 more source

Extranodal Natural Killer/T-Cell Lymphoma Mimicking Chronic Mucormycosis. [PDF]

Laryngoscope
Yun J, Lin ME, Madrigal J, Tyagi R, Ni G, Chia JJ, Kang R.   +6 more
europepmc   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Frequent Novel Viral Focal Copy Number Gains Potentiate Radiosensitivity in Natural Killer/T-Cell Lymphoma. [PDF]

Cancer Commun (Lond)
Lim JQ, Phyu T, Huang D, Phang BH, Fang Z, Ye KCX, Taib NABM, Ng WY, Wong JXN, Lee W, Huifen KML, Wang LW, Peng RJ, Xia Y, Li YQ, Jeyasekharan A, Tan SY, Cheng CL, Somasundaram N, Ong SY, Chng WJ, Lee B, Leong SM, Rötzschke O, Shih LY, Tan J, Chan JY, Xiong J, Zhao WL, Yao F, Liu J, Lim ST, Bei JX, Cheok CF, Ng SB, Ong CK.   +35 more
europepmc   +1 more source

A Metal‐Polyphenol Self‐Assembled Coated 3D Sponge With Mild Photothermal Antibacterial, Exudate‐Controlling, and Immunomodulatory Functions for Hemostasis and Chronic Wound Healing

Advanced Science, EarlyView.
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang, Feng Qin, Xiaomeng Zhang, Xueqin Shuang, Jiahua Zhou, Ming Cheng, Baicheng Lu, Mingyue Song, Yuntian Bai, Dianying Zhang, Ming Li, Yanhua Wang   +11 more
wiley   +1 more source

Extranodal Natural Killer/T-Cell Lymphoma Presenting as Intestinal Stenosis and Perforation. [PDF]

Gastro Hep Adv
Li H, Yao L, Ouzhu M.
europepmc   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

Treatment Patterns and Clinical Outcomes After Immunotherapy Failure in Patients With Natural Killer/T-Cell Lymphoma. [PDF]

Am J Hematol
Bai S, Song Y, Wang L, Liu F, Li Y, Qi S, Peng Z, Zhao Y, Huang H, Xia Y, Bai B, Fang X, Nie M, Cai J, Cao Y, Gao X, Zou Q, Cai Q, Zhang Y.   +18 more
europepmc   +1 more source