Results 21 to 30 of about 224,959 (265)
Linking inflammation to natural killer T cell activation.
PLoS Biology, 2009 Immune activation is often associated with inflammation, but inflammation's role in the expansion of antigen-specific immune responses remains unclear. This primer focuses on recent findings that show how specific natural killer T cells are activated by ...
Mariolina Salio, Vincenzo Cerundolo
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Journal of Medical Case Reports, 2021 Introduction Extranodal, natural-killer/T-cell lymphoma of nasal type is a rare but aggressive disease usually presenting as progressive necrotic lesions in the nasal cavity that responds poorly to chemotherapy.
Fatemeh Adabifirouzjaei +3 more
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PLoS ONE, 2019 Glioblastoma is the leading malignant glioma with a poor prognosis. This study aimed to investigate the antitumor effects of natural killer cells in combination with temozolomide as the standard chemotherapeutic agent for glioblastoma.
Yoshitaka Tanaka +12 more
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Natural killer T cells in health and disease [PDF]
Frontiers in Bioscience, 2011 Natural killer T (NKT) cells are a subset of T lymphocytes that share surface markers and functional characteristics with both conventional T lymphocytes and natural killer cells. Most NKT cells express a semi-invariant T cell receptor that reacts with glycolipid antigens presented by the major histocompatibility complex class I-related protein CD1d on
Lan, Wu, Luc, Van Kaer
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Dynamic Natural Killer Cell and T Cell Responses to Influenza Infection
Frontiers in Cellular and Infection Microbiology, 2020 Influenza viruses have perplexed scientists for over a hundred years. Yearly vaccines limit their spread, but they do not prevent all infections. Therapeutic treatments for those experiencing severe infection are limited; further advances are held back ...
Kayla Frank +3 more
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Natural killer T cells and the regulation of asthma [PDF]
Mucosal Immunology, 2009 A crucial role has been suggested for invariant natural killer T cells (iNKT) in regulating the development of asthma, a complex and heterogeneous disease characterized by airway inflammation and airway hyperreactivity (AHR). iNKT cells constitute a unique subset of T cells responding to endogenous and exogenous lipid antigens, rapidly secreting a ...
P, Matangkasombut +3 more
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Frequent Mutations in Natural Killer/T Cell Lymphoma
Cellular Physiology and Biochemistry, 2018 Extranodal natural killer (NK)/T cell lymphoma (ENKTL-NT or NKTCL), with its aggressive nature and poor prognosis, has been widely studied to discover more effective treatment options.
Yanjie Zhang +4 more
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Reduced NK cell IFN-γ secretion and psychological stress are independently associated with herpes zoster. [PDF]
PLoS ONE, 2018 The pathogenesis of herpes zoster is closely linked to reduced varicella-zoster virus-specific cell-mediated immunity. However, little is known about the interplay between natural killer cells and psychological stress in the pathogenesis of herpes zoster.
Choon Kwan Kim +5 more
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Natural killer T cells: Know thyself [PDF]
Proceedings of the National Academy of Sciences, 2007 There are two main reasons why natural killer T (NKT) cells fascinate immunologists. First, they exhibit a unique melange of properties found in innate immune cells as well as the properties of conventional T cells, part of adaptive immunity (1–4). Second, NKT cells exercise a determining influence on a variety of immune responses in mice, ranging from
Mitchell, Kronenberg, Laurent, Gapin
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Haematologica, 2010 Background Natural killer cells have been demonstrated to exert remarkable graft-versus-leukemia effects after haploidentical transplantation. Acquisition of both, inhibiting and activating, receptors on developing natural killer cells is an important ...
Matthias M. Pfeiffer +6 more
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