Results 61 to 70 of about 213,838 (267)

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Development of invariant natural killer T cells [PDF]

Current Opinion in Immunology, 2016
Invariant natural killer T (iNKT) cells develop into functionally distinct subsets. Each subset expresses a unique combination of transcription factors that regulate cytokine gene transcription upon activation. The tissue distribution and localization within tissues also varies between subsets. Importantly, the relative abundance of the various subsets
openaire   +2 more sources

Natural Killer T Cells in Cancer Immunotherapy [PDF]

Frontiers in Immunology, 2017
Natural killer T (NKT) cells are specialized CD1d-restricted T cells that recognize lipid antigens. Following stimulation, NKT cells lead to downstream activation of both innate and adaptive immune cells in the tumor microenvironment. This has impelled the development of NKT cell-targeted immunotherapies for treating cancer.
Nair, Shiny, Dhodapkar, Madhav V.
openaire   +3 more sources

Epstein-Barr Virus-Positive Natural Killer/T-Cell Lymphoma

Frontiers in Oncology, 2019
Extranodal natural killer/T-cell lymphoma, nasal type (ENKL), is a rare malignancy of Non-Hodgkin lymphoma characterized by an aggressive clinical course and poor prognosis.
Qingqing Cai, Qingqing Cai, Jun Cai, Jun Cai, Yu Fang, Yu Fang, Ken H. Young   +6 more
doaj   +1 more source

Clinical and immunological characteristics for BK polyomavirus‐associated nephropathy after kidney transplantation

Immunity, Inflammation and Disease, 2023
Introduction BK polyomavirus (BKPyV)‐associated nephropathy (BKPyVAN) can cause a significant risk of allograft impairment after kidney transplantation (KT). Intact BKPyV‐specific immunity is associated with viral containment.
Tanaya Siripoon, Nopporn Apiwattanakul, Pannawat Mongkolrattanakul, Chutatip Tongsook, Nattawut Unwanatham, Suradej Hongeng, Surasak Kantachuvesiri, Jackrapong Bruminhent   +7 more
doaj   +1 more source

Nasal Natural Killer/T Cell Lymphoma [PDF]

Indian Journal of Hematology and Blood Transfusion, 2014
Nasal natural killer/T cell lymphomas are locally destructive mid-facial necrotizing lesions. It is an uncommon disease but, usually shows a highly aggressive clinical course. Amongst the sino-nasal lymphomas, it is the most common type. The non-specific clinical features constitute a major stumbling block in the early diagnosis and management of these
Milind Anil, Bhatkule, Manjusha Shripad, Dhawle, N R, Kumbhakarna, Rajan S, Bindu   +3 more
openaire   +2 more sources

Nasal-Type Natural Killer/T-Cell Extranodal Lymphoma

Sinusitis
Nasal-type extranodal natural killer/T-cell lymphoma (ENKTL) is a rare, aggressive non-Hodgkin lymphoma associated with the Epstein–Barr virus (EBV). It predominantly affects middle-aged men and is most common in East Asia and Latin America.
Mustapha Sellami, Sofiane Amazigh Akbal, Lycia Zaidi, Abderrahmane Akacha   +3 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Non-coding RNAs in Natural Killer/T-Cell Lymphoma

Frontiers in Oncology, 2019
Natural killer/T-cell lymphoma (NKTCL) is a rare and aggressive subtype of non-Hodgkin's lymphoma that is associated with a poor outcome. Non-coding RNAs (ncRNAs), which account for 98% of human RNAs, lack the function of encoding proteins but instead ...
Mei Mei, Mei Mei, Mingzhi Zhang
doaj   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source