Results 111 to 120 of about 371,435 (345)
Haematologica, 2009 Background Bortezomib is a selective and potent inhibitor of the proteasome and has prominent effects in vitro and in vivo against tumors. Very recently, cytotoxic effects of bortezomib on immune-competent cells such as T cells and dendritic cells were ...
Xiangling Wang +7 more
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Tumor rejection by the poliovirus receptor family ligands of the DNAM-1(CD226) receptor [PDF]
, 2006 The poliovirus receptor CD155 and its family member CD112 (nectin-2) are the ligands for the activating cell-surface receptor DNAM-1 on CD8(+) T cells and natural killer (NK) cells. Here, we demonstrate that, whereas the RMA tumor grew in syngeneic mice,
Honda Shin-ichiro +12 more
core +1 more source
Primary Orbital Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type, without Nasal Involvement [PDF]
, 2022 Dalan Jing +3 more
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Arthritis Care &Research, Accepted Article.Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah +8 more
wiley +1 more source
Molecular CancerNatural killer (NK) cells are important immune cells in the organism and are the third major type of lymphocytes besides T cells and B cells, which play an important function in cancer therapy.
Chaohua Si, Jianen Gao, Xu Ma
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Recognition of microbial glycolipids by Natural Killer T cells
Frontiers in Immunology, 2015 T cells can recognize microbial antigens when presented by dedicated antigen-presenting molecules. While peptides are presented by classical members of the Major Histocompatibility (MHC) family (MHC I and II), lipids, glycolipids and lipopeptides can be ...
Dirk Michael Zajonc, Enrico eGirardi
doaj +1 more source
Vitamin A-treated natural killer cells reduce interferon-gamma production and support regulatory T cell differentiation [PDF]
, 2022 Mingeum Jeong +4 more
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Advanced Functional Materials, EarlyView.Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou +11 more
wiley +1 more source
Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion
Cell Reports, 2019 Summary: Despite the clinical success of cancer immunotherapies, the majority of patients fail to respond or develop resistance through disruption of pathways that promote neo-antigen presentation on MHC I molecules.
Andrew J. Freeman +8 more
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Natural killer T cells in pulmonary disorders
Respiratory Medicine, 2011 Natural killer T (NKT) cells, a unique subgroup of lymphocytes with features of both T and natural killer (NK) cells, represent a bridge between innate and adaptive immunity. They have the ability to either promote or suppress immune responses. With these immunoregulatory functions, NKT cells have emerged as an important subset of lymphocytes with a ...
Rijavec, Matija +4 more
openaire +4 more sources