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Natural killer cells regulate diverse T cell responses
Trends in Immunology, 2013Natural killer (NK) cells are important mediators of the immune response against microbial pathogens and tumors. There is growing evidence from mouse and human studies that, NK cells exhibit immunoregulatory functions and can limit T cell immunity. NK cell regulatory activity has been demonstrated in a variety of disease models including chronic viral ...
Crome, Sarah Q +3 more
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Natural Killer T Cells in Mucosal Homeostasis
Annals of the New York Academy of Sciences, 2004Abstract: The mucosal‐associated lymphoid tissues (MALT), including the gut‐associated lymphoid tissues, are a tightly regulated environment. In fact, it might be stated that on the basis of studies from animal models of inflammatory bowel disease (IBD), the major means of peripheral regulation of immune responses in the intestine is not necessarily ...
Arthur, Kaser +6 more
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Imaging natural killer T cells in action
Immunology & Cell Biology, 2013Natural killer T (NKT) cells were first recognized more than two decades ago as a distinct lymphocyte lineage that regulates a broad range of immune responses. The activation of NKT cells paradoxically can lead to either suppression or stimulation of immune responses, but despite this uncertainty, many investigators are hopeful that immune therapies ...
Connie H Y, Wong, Paul, Kubes
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Natural killer T cells and ulcerative colitis
Cellular Immunology, 2019Ulcerative colitis (UC) is one of the two major forms of inflammatory bowel disease (IBD). Both innate immunity and adaptive immunity are aberrant in IBD. The pathogenesis of UC includes abnormal inflammation and immune responses of the digestive tract.
Li Jie, Lai, Jun, Shen, Zhi Hua, Ran
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Natural Killer T Cells and Autoimmune Disease
Current Molecular Medicine, 2009Natural killer T (NKT) cells are an unusual subset of innate immune cells that express a surface receptor generated by somatic DNA rearrangement, a hallmark of cells of the adaptive immune system. NKT cells express a highly restricted repertoire of T cell receptors that recognize glycolipid antigens bound with the antigen-presenting molecule CD1d.
Lan, Wu, Luc, Van Kaer
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Nasal natural killer/T‐cell lymphoma
Otolaryngology–Head and Neck Surgery, 2010Che-Yi, Lin, Po-Wen, Cheng
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T/natural killer–cell lymphomas
Journal of the American Academy of Dermatology, 2005Karan K. Sra +5 more
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T/natural killer-cell lymphomas
Journal of the American Academy of Dermatology, 2004Karan K. Sra +3 more
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