Results 61 to 70 of about 371,435 (345)

Comprehensive analysis of peripheral T-cell and natural killer/T-cell lymphoma in Asian patients: A multinational, multicenter, prospective registry study in Asia [PDF]

, 2021
Sang Eun Yoon, Yuqin Song, Seok Jin Kim, Dok Hyun Yoon, Tsai‐Yun Chen, Youngil Koh, Ka‐Won Kang, Ho Sup Lee, Kevin Tay, Soon Thye Lim, M. Poon, Cosphiadi Irawan, Weili Zhao, Young Rok, Mark Hong Lee, Soo Chin Ng, Won Sik Lee, Ye Guo, Huilai Zhang, Hye Jin Kang, Hwan‐Jung Yun, Hyo Jung Kim, Daryl Tan Chen Lung, Jae-Yong Kwak, Jae Joon Han, Yeung‐Chul Mun, Sung Yong Oh, Hyeok Shim, Jung Hye Kwon, Byeong Seok Sohn, Seong Kyu Park, Jae-Cheol Jo, Young Hyeh Ko, Zhu Jun, Won Seog Kim   +34 more
openalex   +1 more source

Natural Killer T Cell Diversity and Immunotherapy

Cancers, 2023
Invariant natural killer T cells (iNKTs), a type of unconventional T cells, share features with NK cells and have an invariant T cell receptor (TCR), which recognizes lipid antigens loaded on CD1d molecules, a major histocompatibility complex class I (MHC-I)-like protein.
Eduardo I. Tognarelli, Cristián Gutiérrez-Vera, Pablo A. Palacios, Ignacio A. Pasten-Ferrada, Fernanda Aguirre-Muñoz, Daniel A. Cornejo, Pablo A. González, Leandro J. Carreño   +7 more
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Antigen specificity of invariant natural killer T-cells

Biomedical Journal, 2015
Natural killer T-cells, with an invariant T-cell antigen receptor α-chain (iNKT cells), are unique and conserved subset of lymphocytes capable of altering the immune system through their rapid and potent cytokine responses.
Alysia M. Birkholz, Mitchell Kronenberg
doaj   +1 more source

RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. [PDF]

, 2012
The NKG2D stimulatory receptor expressed by natural killer cells and T cell subsets recognizes cell surface ligands that are induced on transformed and infected cells and facilitate immune rejection of tumor cells.
Hsiung, Benjamin, Jung, Heiyoun, Pestal, Kathleen, Procyk, Emily, RAULET, David H.   +4 more
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Hepatitis E Virus Infection—Immune Responses to an Underestimated Global Threat

Cells, 2021
Infection with the hepatitis E virus (HEV) is one of the main ubiquitous causes for developing an acute hepatitis. Moreover, chronification plays a predominant role in immunocompromised patients such as transplant recipients with more frequent severe ...
Paul Kupke, Jens M. Werner
doaj   +1 more source

T-cell lymphoma in South America and Europe. [PDF]

, 2012
Peripheral T-cell lymphomas are a group of rare neoplasms originating from clonal proliferation of mature post-thymic lymphocytes with different entities having specific biological characteristics and clinical features.
BELLEI, Monica, Cabrera M. E., Chiattone C. S., Connors J. M., de Souza A. C., FEDERICO, Massimo, Foss F. M., Gabùs R., Horwitz S. M., Liang R., LUMINARI, Stefano, Milone J., Montolo S., Pavlovsky A., PESCE, Emanuela Anna, Pileri S. A., Polliak A., Vose J. M., Zinzani P. L., Zoppegno L., Zucca E.   +20 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Cytokine-induced killer cells are type II natural killer T cells

GMS German Medical Science, 2007
Background: Until now, cytokine-induced killer (CIK) cells were assumed to be part of the type I natural killer T (NKT) cell population, but it was not yet investigated if this is correct.
Schmidt-Wolf, Ingo G.H., Strehl, John, Frank, Susanne, Gütgemann, Stefan   +3 more
doaj