Results 101 to 110 of about 12,812,869 (370)
Media Peternakan, 2017 The aim of the study was to identify the cholesterol-lowering activity of indigenous lactic acid bacteria isolated from the small intestine, cecum, and colon of Indonesian native chickens and evaluated for bile salt hydrolase (BSH) activity in vitro by ...
H. Julendra +5 more
doaj +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
MicrobiologyOpen, 2021 Although diatoms have been utilized as a cellular factory to produce biopharmaceuticals, recombinant proteins, and biofuels, only a few numbers of gene promoters are available. Therefore, the development of novel endogenous promoters is essential for the
Erdenedolgor Erdene‐Ochir +6 more
doaj +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Optimized psilocybin production in tryptophan catabolism‐repressed fungi
Microbial BiotechnologyThe high therapeutic potential of psilocybin, a prodrug of the psychotropic psilocin, holds great promise for the treatment of mental disorders such as therapy‐refractory depression, alcohol use disorder and anorexia nervosa.
Slavica Janevska +12 more
doaj +1 more source
Frontiers in Microbiology, 2015 Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe infections with invasive growth in immunocompromised patients. The fungal cell wall prevents the cell from lysing and protects the fungus against environmental stress ...
Vito eValiante +3 more
doaj +1 more source
Natural Product Communications
Natural Product Communications, 2018 i folium, fiiifolinol acetate, crystal structure, absolute configuration, vibrational circular dichroism, density functional theory calculations.
Fiiifolinol Acetate, P. Joseph-Nathan
semanticscholar +1 more source
Natural Product ReportsA comprehensive review of 1220 new MNPs including a novel sex inducing pheromone from the diatom Seminavis robusta.
Anthony R. Carroll +4 more
openaire +4 more sources
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Development of Paku Hata Craft Products in Citumang, West Java [PDF]
, 2019 Lygodium flexuosum (L.) Sw. (Schizaeaceae) or paku hata is grown in West Java, especially in Citumang, Pangandaran Regency. The local community of Citumang use paku hata as the main materials to produce crafts such as bracelet, hat, bag, wall hanging ...
Ciptandi, F. (Fajar ) +1 more
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