Results 91 to 100 of about 8,248,717 (265)
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Frontiers in Microbiology, 2011 Aspergillus fumigatus is the most important air-borne fungal pathogen of humans. The interaction of the pathogen with the host’s immune system represents a key process to understand pathogenicity.
Andreas eThywißen +9 more
doaj +1 more source
Bisabolenes and Nor- sesquiterpenes from Bazzania tridens
, 2010 Two bisabolene sesquiterpenes (1 and 2), two nor-sesquiterpene ketones (3 and 4) and one humulene epoxide (6) were identified from the Taiwanese liverwort Bazzania tridens.
吳嘉麗; Wu, Chia-li; Chen, Wei-yu; Chu, Chi-sheng
core +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Data-based reconstruction of gene regulatory networks of fungal pathogens
Frontiers in Microbiology, 2016 In the emerging field of systems biology of fungal infection, one of the central roles belongs to the modelling of gene regulatory networks (GRNs). Utilising omics-data, GRNs can be predicted by mathematical modelling. Here, we review current advances of
Reinhard eGuthke +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
How to predict molecular interactions between species?
Frontiers in Microbiology, 2016 Organisms constantly interact with other species through physical contact which leads to chan-ges on the molecular level, for example the transcriptome. These changes can be monitored forall genes, with the help of high-throughput experiments such as RNA-
Jörg eLinde +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
An infinite natural product [PDF]
, 2018 We study a countably infinite iteration of the natural product between ordinals. We present an “effective” way to compute this countable natural product; in the non trivial cases the result depends only on the natural sum of the degrees of the factors ...
Lipparini, Paolo
core +3 more sources
Media Peternakan, 2017 The aim of the study was to identify the cholesterol-lowering activity of indigenous lactic acid bacteria isolated from the small intestine, cecum, and colon of Indonesian native chickens and evaluated for bile salt hydrolase (BSH) activity in vitro by ...
H. Julendra +5 more
doaj +1 more source